Claudin 11 Antikörper (C-Term)

Produktnummer ABIN2778048

Der Kaninchen Polyklonal anti-Claudin 11 Antikörper (ABIN2778048) detektiert spezifisch Claudin 11 in WB und IHC. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus, Ratte, Rind (Kuh), Hund, Kaninchen, Meerschweinchen und Pferd.

Kurzübersicht für Claudin 11 Antikörper (C-Term) (ABIN2778048)

Target: Claudin 11 (CLDN11)

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Kaninchen, Meerschweinchen, Pferd

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Claudin 11 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-Claudin 11 Antikörper

Bindungsspezifität: C-Term

Verwendungszweck: CLDN11 Antibody - C-terminal region

Sequenz: VSFGYSLYAG WIGAVLCLVG GCVILCCAGD AQAFGENRFY YTAGSSSPTH

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 86%, Rabbit: 100%, Rat: 86%

Produktmerkmale: This is a rabbit polyclonal antibody against CLDN11. It was validated on Western Blot and immunohistochemistry.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human CLDN11

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under ABIN8097495

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Details zu Claudin 11

Target: Claudin 11 (CLDN11)

Andere Bezeichnung: CLDN11

Hintergrund:

Background Information: CLDN11 belongs to the claudin family of tight junction associated proteins and is a major component of central nervous system myelin that is necessary for normal CNS function. There is growing evidence that the protein determines the permeability between layers of myelin sheaths via focal adhesion and, with its expression highly regulated during development, may play an important role in cellular proliferation and migration. In addition, the protein is a candidate autoantigen in the development of autoimmune demyelinating disease.The protein encoded by this gene belongs to the claudin family of tight junction associated proteins and is a major component of central nervous system myelin that is necessary for normal CNS function. There is growing evidence that the protein determines the permeability between layers of myelin sheaths via focal adhesion and, with its expression highly regulated during development, may play an important role in cellular proliferation and migration. In addition, the protein is a candidate autoantigen in the development of autoimmune demyelinating disease.

Gene Name: Claudin 11

Alternative Symbols: OSP, OTM

Protein Name: Claudin-11

Molekulargewicht: 22kDa

Gen-ID: 5010

NCBI Accession: NP_005593

UniProt: O75508

Pathways: Hepatitis C