TULP1 Antikörper (Middle Region)
Kurzübersicht für TULP1 Antikörper (Middle Region) (ABIN2777956)
Target
Alle TULP1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- Middle Region
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Sequenz
- EEEEAATVIK KSNQKGKAKG KGKKKAKEER APSPPVEVDE PREFVLRPAP
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Homologie
- Cow: 100%, Dog: 100%, Guinea Pig: 91%, Horse: 100%, Human: 100%, Mouse: 85%, Rabbit: 100%, Rat: 91%, Yeast: 100%
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Produktmerkmale
- This is a rabbit polyclonal antibody against TULP1. It was validated on Western Blot using a cell lysate as a positive control.
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Aufreinigung
- Affinity Purified
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Immunogen
- The immunogen is a synthetic peptide directed towards the middle region of human TULP1
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Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
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Kommentare
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Antigen size: 542 AA
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- Lot specific
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid repeated freeze-thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- TULP1 (Tubby Like Protein 1 (TULP1))
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Andere Bezeichnung
- TULP1
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Hintergrund
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TULP1 is required for normal development of photoreceptor synapses. TULP1 is also required for normal photoreceptor function and for long-term survival of photoreceptor cells. TULP1 interacts with cytoskeleton proteins and may play a role in protein transport in photoreceptor cells. TULP1 binds lipids, especially phosphatidylinositol-3-phosphate, phosphatidylinositol-4-phosphate, phosphatidylinositol-5-phosphate, phosphatidylinositol-3,4-bisphosphate, phosphatidylinositol-4,5-bisphosphate, phosphatidylinositol-3,4,5-bisphosphate, phosphatidylserine and phosphatidic acid (in vitro).This gene encodes a member of the tubby-like gene family (TULPs). Members of this family have been identified in plants, vertebrates, and invertebrates and encode proteins of unknown function. TULP proteins share a conserved C-terminal region of approximately 200 amino acid residues. Mutations in this gene may be associated with retinitis pigmentosa. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: RP14, TUBL1, LCA15
Protein Size: 542 -
Molekulargewicht
- 60 kDa
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Gen-ID
- 7287
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NCBI Accession
- NM_003322, NP_003313
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UniProt
- O00294
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Pathways
- RTK Signalweg
Target
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