MRGBP Antikörper (Middle Region)

Produktnummer ABIN182784

Produktdetails anti-MRGBP Antikörper

Target: MRGBP (MRG-Binding Protein (MRGBP))

Bindungsspezifität: Middle Region

Reaktivität: Human, Maus, Meerschweinchen, Ratte, Rind (Kuh), Zebrafisch (Danio rerio), Pferd, Hund

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MRGBP Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: LSTMYDMQAL HESEILPFPN PERNFVLPEE IIQEVREGKV MIEEEMKEEM

Homologie: Cow: 93%, Dog: 93%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 93%, Rat: 100%, Zebrafish: 79%

Produktmerkmale: This is a rabbit polyclonal antibody against C20ORF20. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human C20ORF20

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 204 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu MRGBP

Target: MRGBP (MRG-Binding Protein (MRGBP))

Andere Bezeichnung: C20ORF20 (MRGBP Produkte)

Hintergrund: C20orf20 belongs to the EAF7 family. It is a component of the NuA4 histone acetyltransferase (HAT) complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histone H4 and H2A. This complex may be required for the activation of transcriptional programs associated with oncogene and proto-oncogene mediated growth induction, tumor suppressor mediated growth arrest and replicative senescence, apoptosis, and DNA repair. NuA4 may also play a direct role in DNA repair when recruited to sites of DNA damage.
Alias Symbols: Eaf7, MRGBP, URCC4, MRG15BP, C20ORF20
Protein Interaction Partner: MORF4L1, MORF4L2, NOTCH2NL, KRTAP10-7, H2AFZ, ELAVL1, SH3BP4, VAV2, UBC, H2AFV, MRFAP1, EPC1, DMAP1, MRGBP, MBTD1, EPC2, SIN3B, BRD8, RUVBL2, SRCAP, KAT5, RUVBL1, HIST2H2BE, TUBA1A, TUBB2A, RBBP7, HNRNPM, LMNA, KPNA2, KPNB1, HSPA4, HNRNPU, HNRNPK, ACTL6A,
Protein Size: 204

Molekulargewicht: 22 kDa

Gen-ID: 55257

NCBI Accession: NM_018270, NP_060740

UniProt: Q9NV56