Sp3 Antikörper (N-Term)

Produktnummer ABIN2777873

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch Sp3 in WB. Er zeigt eine Reaktivität gegenüber Human, Maus, Ratte, Meerschweinchen, Pferd, Kaninchen, Rind (Kuh) und Hund.

Kurzübersicht für Sp3 Antikörper (N-Term) (ABIN2777873)

Target: Sp3 (Sp3 Transcription Factor (Sp3))

Reaktivität: Human, Maus, Ratte, Meerschweinchen, Pferd, Kaninchen, Rind (Kuh), Hund

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Sp3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-Sp3 Antikörper

Bindungsspezifität: N-Term

Sequenz: SSSSQLPVTI DSTGILQQNT NSLTTSSGQV HSSDLQGNYI QSPVSEETQA

Homologie: Cow: 93%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 93%, Rabbit: 100%, Rat: 93%

Produktmerkmale: This is a rabbit polyclonal antibody against SP3. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Human SP3

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeat freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu Sp3

Target: Sp3 (Sp3 Transcription Factor (Sp3))

Andere Bezeichnung: SP3

Hintergrund: This gene belongs to a family of Sp1 related genes that encode transcription factors that regulate transcription by binding to consensus GC- and GT-box regulatory elements in target genes. This protein contains a zinc finger DNA-binding domain and several transactivation domains, and has been reported to function as a bifunctional transcription factor that either stimulates or represses the transcription of numerous genes. Transcript variants encoding different isoforms have been described for this gene, and one has been reported to initiate translation from a non-AUG (AUA) start codon. Additional isoforms, resulting from the use of alternate downstream translation initiation sites, have also been noted. A related pseudogene has been identified on chromosome 13.
Protein Interaction Partner: SP1, SUMO1, PPP2R4, PPP1CC, GCH1, HLTF, TFAP4, YY1, SUMO2, UBC, RELA, MECP2, HDAC2, HDAC1, ZBTB7B, EP300, CRX, TP53, NKX3-1, CREBBP, CEBPB, ESR1, DNMT1, SFPQ, PIAS1, GRIN1, GABPA, ZBTB7A, UBE2I, STK19, RBBP4, E2F1, RB1, SP4, TNFSF10, SENP1,
Protein Size: 479

Molekulargewicht: 52 kDa

Gen-ID: 6670