Endoglin Antikörper (N-Term)

Produktnummer ABIN2777735

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch Endoglin in WB und IHC. Er zeigt eine Reaktivität gegenüber Human, Maus, Ratte und Meerschweinchen.

Kurzübersicht für Endoglin Antikörper (N-Term) (ABIN2777735)

Target: Endoglin (ENG)

Reaktivität: Human, Maus, Ratte, Meerschweinchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Endoglin Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-Endoglin Antikörper

Bindungsspezifität: N-Term

Sequenz: ILEVHVLFLE FPTGPSQLEL TLQASKQNGT WPREVLLVLS VNSSVFLHLQ

Homologie: Guinea Pig: 91%, Human: 100%, Mouse: 91%, Rat: 91%

Produktmerkmale: This is a rabbit polyclonal antibody against ENG. It was validated on Western Blot and immunohistochemistry.

Aufreinigung: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human ENG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 625 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu Endoglin

Target: Endoglin (ENG)

Andere Bezeichnung: ENG

Hintergrund: Endoglin is a homodimeric transmembrane glycoprotein highly expressed by endothelial cells. It is a component of the transforming growth factor beta receptor complex since it binds TGFB1 and TGFB3 with high affinity. Mutations in the endoglin gene produce hereditary hemorrhagic telangiectasia.
Alias Symbols: END, ORW, HHT1, ORW1, CD105
Protein Interaction Partner: ENG, TGFBR2, TGFBR1, TGFB3, TGFB1, ACVRL1, TUFM, TCTEX1D4, TGFBR3, TGFB2, INHBA, BMP7, BMP2, ACVR2A, ACVR1, ACVR2B,
Protein Size: 625

Molekulargewicht: 68 kDa

Gen-ID: 2022

NCBI Accession: NM_000118, NP_000109

UniProt: P17813