POLE3 Antikörper (N-Term)
Kurzübersicht für POLE3 Antikörper (N-Term) (ABIN2777723)
Target
Alle POLE3 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- N-Term
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Sequenz
- MAERPEDLNL PNAVITRIIK EALPDGVNIS KEARSAISRA ASVFVLYATS
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Homologie
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 85%
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Produktmerkmale
- This is a rabbit polyclonal antibody against POLE3. It was validated on Western Blot using a cell lysate as a positive control.
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Aufreinigung
- Protein A purified
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Immunogen
- The immunogen is a synthetic peptide directed towards the N terminal region of human POLE3
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Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
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Kommentare
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Antigen size: 147 AA
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- Lot specific
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid repeated freeze-thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- POLE3 (Polymerase (DNA Directed), epsilon 3 (p17 Subunit) (POLE3))
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Andere Bezeichnung
- POLE3
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Hintergrund
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POLE3 is a histone-fold protein that interacts with other histone-fold proteins to bind DNA in a sequence-independent manner. These histone-fold protein dimers combine within larger enzymatic complexes for DNA transcription, replication, and packaging.
Alias Symbols: p17, YBL1, CHRAC17, CHARAC17
Protein Interaction Partner: CHRAC1, DRAP1, DR1, UBC, NANS, ANXA6, gag-pol, POLE4, CPSF2, POLE, APP, YEATS2, POLE2, Cebpb, SUMO2, XRCC5, BAZ1A, SMARCA5, RAD17,
Protein Size: 147 -
Molekulargewicht
- 17 kDa
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Gen-ID
- 54107
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NCBI Accession
- NM_017443, NP_059139
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UniProt
- Q9NRF9
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Pathways
- DNA Reparatur
Target
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