Aprataxin Antikörper (N-Term)

Produktnummer ABIN2777649

Der Kaninchen Polyklonal anti-Aprataxin Antikörper (ABIN2777649) detektiert spezifisch Aprataxin in WB und IHC. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus, Ratte, Meerschweinchen, Hund, Pferd und Kaninchen.

Kurzübersicht für Aprataxin Antikörper (N-Term) (ABIN2777649)

Target: Aprataxin (APTX)

Reaktivität: Human, Maus, Ratte, Meerschweinchen, Hund, Pferd, Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Aprataxin Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-Aprataxin Antikörper

Bindungsspezifität: N-Term

Verwendungszweck: APTX Antibody - N-terminal region

Sequenz: MMRVCWLVRQ DSRHQRIRLP HLEAVVIGRG PETKITDKKC SRQQVQLKAE

Homologie: Dog: 85%, Guinea Pig: 86%, Horse: 93%, Human: 100%, Mouse: 93%, Rabbit: 93%, Rat: 93%

Produktmerkmale: This is a rabbit polyclonal antibody against APTX. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human APTX

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under ABIN8094861

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1.0 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Details zu Aprataxin

Target: Aprataxin (APTX)

Andere Bezeichnung: APTX

Hintergrund:

Background Information: APTX is a member of the histidine triad (HIT) superfamily, some of which have nucleotide-binding and diadenosine polyphosphate hydrolase activities. APTX may play a role in single-stranded DNA repair. Mutations in this gene have been associated with ataxia-ocular apraxia.This gene encodes a member of the histidine triad (HIT) superfamily, some of which have nucleotide-binding and diadenosine polyphosphate hydrolase activities. The encoded protein may play a role in single-stranded DNA repair. Mutations in this gene have been associated with ataxia-ocular apraxia. Multiple transcript variants encoding distinct isoforms have been identified for this gene, however, the full length nature of some variants has not been determined.

Gene Name: Aprataxin

Alternative Symbols: AOA, AOA1, AXA1, EAOH, EOAHA, FHA-HIT

Protein Name: Aprataxin

Molekulargewicht: 38kDa

Gen-ID: 54840

NCBI Accession: NP_778243

UniProt: Q6JV85

Pathways: DNA Reparatur, Chromatin Binding