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Aprataxin Antikörper (N-Term)

APTX Reaktivität: Human, Maus, Ratte, Meerschweinchen, Hund, Kaninchen, Pferd WB, IHC Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN2777649
  • Target Alle Aprataxin (APTX) Antikörper anzeigen
    Aprataxin (APTX)
    Bindungsspezifität
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reaktivität
    • 30
    • 13
    • 13
    • 4
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    Human, Maus, Ratte, Meerschweinchen, Hund, Kaninchen, Pferd
    Wirt
    • 26
    • 4
    Kaninchen
    Klonalität
    • 27
    • 3
    Polyklonal
    Konjugat
    • 19
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser Aprataxin Antikörper ist unkonjugiert
    Applikation
    • 17
    • 9
    • 7
    • 6
    • 3
    • 3
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    Sequenz
    MMRVCWLVRQ DSRHQRIRLP HLEAVVIGRG PETKITDKKC SRQQVQLKAE
    Homologie
    Dog: 85%, Guinea Pig: 86%, Horse: 93%, Human: 100%, Mouse: 93%, Rabbit: 93%, Rat: 93%
    Produktmerkmale
    This is a rabbit polyclonal antibody against APTX. It was validated on Western Blot using a cell lysate as a positive control.
    Aufreinigung
    Protein A purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the N terminal region of human APTX
    Top Product
    Discover our top product APTX Primärantikörper
  • Applikationshinweise
    Optimal working dilutions should be determined experimentally by the investigator.
    Kommentare

    Antigen size: 342 AA

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freeze-thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    Aprataxin (APTX)
    Andere Bezeichnung
    APTX (APTX Produkte)
    Synonyme
    aptx antikoerper, APTX antikoerper, LOC100284636 antikoerper, APRATAXIN-like antikoerper, T10O8.20 antikoerper, T10O8_20 antikoerper, AOA antikoerper, AOA1 antikoerper, AXA1 antikoerper, EAOH antikoerper, EOAHA antikoerper, FHA-HIT antikoerper, 2410016G21Rik antikoerper, AA388047 antikoerper, aprataxin antikoerper, FHA-HIT antikoerper, APRATAXIN-like protein antikoerper, aprataxin L homeolog antikoerper, aptx antikoerper, APTX antikoerper, CpipJ_CPIJ001673 antikoerper, LOC100284636 antikoerper, aptx.L antikoerper, Aptx antikoerper
    Hintergrund
    APTX is a member of the histidine triad (HIT) superfamily, some of which have nucleotide-binding and diadenosine polyphosphate hydrolase activities. APTX may play a role in single-stranded DNA repair. Mutations in this gene have been associated with ataxia-ocular apraxia.This gene encodes a member of the histidine triad (HIT) superfamily, some of which have nucleotide-binding and diadenosine polyphosphate hydrolase activities. The encoded protein may play a role in single-stranded DNA repair. Mutations in this gene have been associated with ataxia-ocular apraxia. Multiple transcript variants encoding distinct isoforms have been identified for this gene, however, the full length nature of some variants has not been determined.
    Alias Symbols: AOA, AOA1, AXA1, EAOH, EOAHA, FHA-HIT
    Protein Interaction Partner: PNMA1, UBC, SUMO1, NEDD8, LIG3, HSPA4, XRCC1, DDX21, CNTROB, TSPYL2, CALCOCO1, SYT17, ZNF639, MAPKBP1, CEP350, PICK1, XRCC4, TRIM37, MBP, HIVEP1, BANF1, PARP1, TP53,
    Protein Size: 342
    Molekulargewicht
    38 kDa
    Gen-ID
    54840
    NCBI Accession
    NM_175073, NP_778243
    UniProt
    Q6JV85
    Pathways
    DNA Reparatur, Chromatin Binding
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