Aprataxin Antikörper (Middle Region)

Produktnummer ABIN2777648

Produktdetails anti-Aprataxin Antikörper

Target: Aprataxin (APTX)

Bindungsspezifität: Middle Region

Reaktivität: Human, Meerschweinchen, Hund, Kaninchen, Pferd, Rind (Kuh)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Aprataxin Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: YPYIVEFEEE AKNPGLETHR KRKRSGNSDS IERDAAQEAE AGTGLEPGSN

Homologie: Cow: 77%, Dog: 86%, Guinea Pig: 79%, Horse: 92%, Human: 100%, Rabbit: 86%

Produktmerkmale: This is a rabbit polyclonal antibody against APTX. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human APTX

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 306 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu Aprataxin

Target: Aprataxin (APTX)

Andere Bezeichnung: APTX (APTX Produkte)

Synonyme: aptx antikoerper, APTX antikoerper, LOC100284636 antikoerper, APRATAXIN-like antikoerper, T10O8.20 antikoerper, T10O8_20 antikoerper, AOA antikoerper, AOA1 antikoerper, AXA1 antikoerper, EAOH antikoerper, EOAHA antikoerper, FHA-HIT antikoerper, 2410016G21Rik antikoerper, AA388047 antikoerper, aprataxin antikoerper, FHA-HIT antikoerper, APRATAXIN-like protein antikoerper, aprataxin L homeolog antikoerper, aptx antikoerper, APTX antikoerper, CpipJ_CPIJ001673 antikoerper, LOC100284636 antikoerper, aptx.L antikoerper, Aptx antikoerper

Hintergrund: APTX is a member of the histidine triad (HIT) superfamily, some of which have nucleotide-binding and diadenosine polyphosphate hydrolase activities. The protein may play a role in single-stranded DNA repair. Mutations in this gene have been associated with ataxia-ocular apraxia. Multiple transcript variants encoding distinct isoforms have been identified for this gene, however, the full length nature of some variants has not been determined. This gene encodes a member of the histidine triad (HIT) superfamily, some of which have nucleotide-binding and diadenosine polyphosphate hydrolase activities. The encoded protein may play a role in single-stranded DNA repair. Mutations in this gene have been associated with ataxia-ocular apraxia. Multiple transcript variants encoding distinct isoforms have been identified for this gene, however, the full length nature of some variants has not been determined.
Alias Symbols: AOA, AOA1, AXA1, EAOH, EOAHA, FHA-HIT, FLJ20157, MGC1072
Protein Interaction Partner: PNMA1, UBC, SUMO1, NEDD8, LIG3, HSPA4, XRCC1, DDX21, CNTROB, TSPYL2, CALCOCO1, SYT17, ZNF639, MAPKBP1, CEP350, PICK1, XRCC4, TRIM37, MBP, HIVEP1, BANF1, PARP1, TP53,
Protein Size: 306

Molekulargewicht: 35 kDa

Gen-ID: 54840

NCBI Accession: NM_175069, NP_778239

UniProt: Q5T782

Pathways: DNA Reparatur, Chromatin Binding