Prohibitin Antikörper (C-Term)

Produktnummer ABIN2777606

Der Kaninchen Polyklonal anti-Prohibitin Antikörper wird verwendet zum Nachweis von Prohibitin in Proben von Human, Maus, Ratte, Zebrafisch (Danio rerio), Meerschweinchen, Kaninchen, Rind (Kuh), Hund und Pferd. Er wurde validiert für WB und IHC.

Kurzübersicht für Prohibitin Antikörper (C-Term) (ABIN2777606)

Target: Prohibitin (PHB)

Reaktivität: Human, Maus, Ratte, Zebrafisch (Danio rerio), Meerschweinchen, Kaninchen, Rind (Kuh), Hund, Pferd

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Prohibitin Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-Prohibitin Antikörper

Bindungsspezifität: C-Term

Verwendungszweck: PHB Antibody - C-terminal region

Sequenz: AEQQKKAAII SAEGDSKAAE LIANSLATAG DGLIELRKLE AAEDIAYQLS

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 86%

Produktmerkmale: This is a rabbit polyclonal antibody against PHB. It was validated on Western Blot and immunohistochemistry.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human PHB

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP32807-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Details zu Prohibitin

Target: Prohibitin (PHB)

Andere Bezeichnung: PHB

Hintergrund:

Background Information: Prohibitin is from an evolutionarily conserved gene that is ubiquitously expressed. It is thought to be a negative regulator of cell proliferation and may be a tumor suppressor. Mutations in PHB have been linked to sporadic breast cancer. Prohibitin is expressed as two transcripts with varying lengths of 3' untranslated region. The longer transcript is present at higher levels in proliferating tissues and cells, suggesting that this longer 3' untranslated region may function as a trans-acting regulatory RNA.

Gene Name: Prohibitin

Alternative Symbols: PHB1, HEL-215, HEL-S-54e

Protein Name: Prohibitin

Molekulargewicht: 30kDa

Gen-ID: 5245

NCBI Accession: NP_002625

UniProt: P35232

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling