PIAS3 Antikörper (Middle Region)
-
- Target Alle PIAS3 Antikörper anzeigen
- PIAS3 (Protein Inhibitor of Activated STAT, 3 (PIAS3))
-
Bindungsspezifität
- Middle Region
-
Reaktivität
- Human, Ratte, Hund, Rind (Kuh), Pferd, Meerschweinchen, Kaninchen
-
Wirt
- Kaninchen
-
Klonalität
- Polyklonal
-
Konjugat
- Dieser PIAS3 Antikörper ist unkonjugiert
-
Applikation
- Western Blotting (WB)
- Sequenz
- DEIQFMEDGS WCPMKPKKEA SEVCPPPGYG LDGLQYSPVQ GGDPSENKKK
- Homologie
- Cow: 79%, Dog: 86%, Guinea Pig: 86%, Horse: 86%, Human: 100%, Rabbit: 79%, Rat: 79%
- Produktmerkmale
- This is a rabbit polyclonal antibody against PIAS3. It was validated on Western Blot using a cell lysate as a positive control.
- Aufreinigung
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the middle region of human PIAS3
- Top Product
- Discover our top product PIAS3 Primärantikörper
-
-
- Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
- Kommentare
-
Antigen size: 628 AA
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
- Format
- Liquid
- Konzentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
-
- Target
- PIAS3 (Protein Inhibitor of Activated STAT, 3 (PIAS3))
- Andere Bezeichnung
- PIAS3 (PIAS3 Produkte)
- Synonyme
- PIAS3 antikoerper, Pias3l antikoerper, ZMIZ5 antikoerper, protein inhibitor of activated STAT 3 antikoerper, protein inhibitor of activated STAT, 3 antikoerper, protein inhibitor of activated STAT 3 L homeolog antikoerper, PIAS3 antikoerper, pias3 antikoerper, Pias3 antikoerper, pias3.L antikoerper
- Hintergrund
-
PIAS3 is a member of the protein inhibitor of activated STAT (PIAS) family. It also activates TGF-beta/SMAD transcriptional responses. This gene encodes a member of the PIAS [protein inhibitor of activated STAT (signal transducer and activator of transcription)] family of transcriptional modulators. The protein functions as a SUMO (small ubiquitin-like modifier)-E3 ligase which catalyzes the covalent attachment of a SUMO protein to specific target substrates. It directly binds to several transcription factors and either blocks or enhances their activity. Alternatively spliced transcript variants of this gene have been identified, but the full-length nature of some of these variants has not been determined. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: FLJ14651, ZMIZ5
Protein Interaction Partner: UBC, HIC1, TRIM63, TRIM55, TAB2, SUMO1, CBS, SUMO2, SUMO3, STAT3, NCOA2, CREM, PRPF40A, SERPINA10, GEMIN4, UBE2I, SKIL, HNRNPK, ZFHX3, SERBP1, SATB1, ERBB4, Bcl11a, ELAVL1, PPP1CA, Grm7, Grm8, Grm6, Grm4, TRIM8, RAC1, C19orf60, CARHSP1, UBA1, PSMC1, TRIM2
Protein Size: 628 - Molekulargewicht
- 68 kDa
- Gen-ID
- 10401
- NCBI Accession
- NM_006099, NP_006090
- UniProt
- Q9Y6X2
- Pathways
- JAK-STAT Signalweg
-