HES1 Antikörper (C-Term)

Produktnummer ABIN2777527

Produktdetails anti-HES1 Antikörper

Target: HES1 (Hes Family bHLH Transcription Factor 1 (HES1))

Bindungsspezifität: C-Term

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Kaninchen, Meerschweinchen, Schwein

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser HES1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: AFLIPNGAFA HSGPVIPVYT SNSGTSVGPN AVSPSSGSSL TADSMWRPWR

Homologie: Cow: 100%, Guinea Pig: 93%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 93%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against Hes1. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide corresponding to a region of Rat

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 281 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu HES1

Target: HES1 (Hes Family bHLH Transcription Factor 1 (HES1))

Andere Bezeichnung: Hes1 (HES1 Produkte)

Synonyme: HES-1 antikoerper, HHL antikoerper, HRY antikoerper, bHLHb39 antikoerper, Hry antikoerper, HAIRY1 antikoerper, c-hairy1A antikoerper, Xhairy1 antikoerper, hairy1 antikoerper, hes1 antikoerper, Xhairy-1 antikoerper, Xlh1 antikoerper, hes family bHLH transcription factor 1 antikoerper, hairy and enhancer of split 1 (Drosophila) antikoerper, hes family bHLH transcription factor 4 antikoerper, hes family bHLH transcription factor 1 S homeolog antikoerper, hes family bHLH transcription factor 1 L homeolog antikoerper, HES1 antikoerper, Hes1 antikoerper, HES4 antikoerper, hes1.S antikoerper, hes1.L antikoerper

Hintergrund: Hes1 is the transcriptional repressor of genes that require a bHLH protein for their transcription. Hes1 may act as a negative regulator of myogenesis by inhibiting the functions of MYOD1 and ASH1. Hes1 binds DNA on N-box motifs: 5'-CACNAG-3' with high affinity and on E-box motifs: 5'-CANNTG-3' with low affinity.
Alias Symbols: Hes1
Protein Interaction Partner: Polr2a, Kat2b, Sfpq, Src, Crebbp, Parp1, Camk2a,
Protein Size: 281

Molekulargewicht: 30 kDa

Gen-ID: 29577

NCBI Accession: NM_024360, NP_077336

UniProt: Q04666

Pathways: DNA Reparatur