FOXA3 Antikörper (Middle Region)

Produktnummer ABIN2777513

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch FOXA3 in WB und IHC. Er zeigt eine Reaktivität gegenüber Human, Hund, Maus, Ratte, Rind (Kuh), Meerschweinchen, Pferd, Kaninchen und Zebrafisch (Danio rerio) und wurde in 1 Publikation erwähnt.

Kurzübersicht für FOXA3 Antikörper (Middle Region) (ABIN2777513)

Target: FOXA3 (Forkhead Box A3 (FOXA3))

Reaktivität: Human, Hund, Maus, Ratte, Rind (Kuh), Meerschweinchen, Pferd, Kaninchen, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FOXA3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-FOXA3 Antikörper

Bindungsspezifität: Middle Region

Sequenz: FENGCYLRRQ KRFKLEEKVK KGGSGAATTT RNGTGSAAST TTPAATVTSP

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 92%, Human: 100%, Mouse: 92%, Rabbit: 85%, Rat: 100%, Zebrafish: 79%

Produktmerkmale: This is a rabbit polyclonal antibody against FOXA3. It was validated on Western Blot and immunohistochemistry.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human FOXA3

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 350 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-FOXA3 Antikörper (ABIN2777513)

Menga, Infantino, Iacobazzi, Convertini, Palmieri, Iacobazzi: "Insight into mechanism of in vitro insulin secretion increase induced by antipsychotic clozapine: role of FOXA1 and mitochondrial citrate carrier." in: European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, Vol. 23, Issue 8, pp. 978-87, (2013) (PubMed).

Details zu FOXA3

Target: FOXA3 (Forkhead Box A3 (FOXA3))

Andere Bezeichnung: FOXA3

Hintergrund: FOXA3 encodes a member of the forkhead class of DNA-binding proteins. These hepatocyte nuclear factors are transcriptional activators for liver-specific transcripts such as albumin and transthyretin, and they also interact with chromatin. Similar family members in mice have roles in the regulation of metabolism and in the differentiation of the pancreas and liver. The crystal structure of a similar protein in rat has been resolved.
Alias Symbols: FKHH3, HNF3G, TCF3G
Protein Interaction Partner: PPARA, ALX4, TLE2, TLE1, HMGB1,
Protein Size: 350

Molekulargewicht: 37 kDa

Gen-ID: 3171

NCBI Accession: NM_004497, NP_004488

UniProt: P55318

Pathways: Carbohydrate Homeostasis