IKZF1 Antikörper (Middle Region)

Produktnummer ABIN2777317

Der Kaninchen Polyklonal anti-IKZF1 Antikörper (ABIN2777317) detektiert spezifisch IKZF1 in WB. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus, Ratte, Hund, Rind (Kuh), Pferd, Meerschweinchen und Kaninchen.

Kurzübersicht für IKZF1 Antikörper (Middle Region) (ABIN2777317)

Target: IKZF1 (IKAROS Family Zinc Finger 1 (Ikaros) (IKZF1))

Reaktivität: Human, Maus, Ratte, Hund, Rind (Kuh), Pferd, Meerschweinchen, Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser IKZF1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-IKZF1 Antikörper

Bindungsspezifität: Middle Region

Sequenz: DLCKIGSERS LVLDRLASNV AKRKSSMPQK FLGDKGLSDT PYDSSASYEK

Homologie: Cow: 92%, Dog: 93%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 93%, Rabbit: 92%, Rat: 93%

Produktmerkmale: This is a rabbit polyclonal antibody against IKZF1. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human IKZF1

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 519 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu IKZF1

Target: IKZF1 (IKAROS Family Zinc Finger 1 (Ikaros) (IKZF1))

Andere Bezeichnung: IKZF1

Hintergrund: IKZF1 binds and activates the enhancer (delta-A element) of the CD3-delta gene. It functions in the specification and the maturation of the T-lymphocyte. It also interacts with a critical control element in the TDT (terminal deoxynucleotidyltransferase) promoter as well as with the promoters for other genes expressed during early stages of B- and T-cell development.
Alias Symbols: Hs.54452, IK1, IKAROS, LYF1, PRO0758, ZNFN1A1, hIk-1
Protein Interaction Partner: PRKAB2, PIN1, FGF12, DDX6, DCX, CTBP2, CTBP1, CKS1B, BYSL, FAM74A4, C1orf174, CEP57L1, ALKBH3, ZMAT2, ZNF417, FRMD6, SPATC1L, FAM161A, FAM214B, ARMC7, NOC4L, SCNM1, C8orf33, AEN, GMCL1P1, KIF9, SH2D4A, CBX8, LMO3, C19orf66, C1orf109, SYT17, ZNF581, FAM50B
Protein Size: 519

Molekulargewicht: 57 kDa

Gen-ID: 10320

NCBI Accession: NM_006060, NP_006051

UniProt: Q13422

Pathways: Production of Molecular Mediator of Immune Response