IKZF1 Antikörper (N-Term)

Produktnummer ABIN2668828

Es gibt 1 Publikation für dieses Produkt. Der Maus Monoklonal anti-IKZF1 Antikörper wird verwendet zum Nachweis von IKZF1 in Proben von Maus. Er wurde validiert für WB, ChIP und ChIP-seq.

Kurzübersicht für IKZF1 Antikörper (N-Term) (ABIN2668828)

Target: IKZF1 (IKAROS Family Zinc Finger 1 (Ikaros) (IKZF1))

Reaktivität: Maus

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser IKZF1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Chromatin Immunoprecipitation (ChIP), ChIP DNA-Sequencing (ChIP-seq)

Klon: 2A9

Produktdetails anti-IKZF1 Antikörper

Bindungsspezifität: N-Term

Verwendungszweck: Ikaros antibody (mAb) (Clone 2A9)

Aufreinigung: Protein G Chromatography

Immunogen: This Ikaros antibody was raised against a recombinant protein corresponding to the N-terminal half of mouse Ikaros.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ChIP: 4 μg per ChIP ChIP-Seq: 4 μg each WB: 0.5 - 2 μg/mL dilution ChIP-Seq validation was performed by Active Motif's Epigenetics Services, the complete data set is available in the UCSC Genome Browser by clicking here.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 μg/μL

Buffer: Purified IgG in 70 mM Tris ( pH 8), 105 mM NaCl, 31 mM glycine, 0.07 mM EDTA, 30 % glycerol and 0.035 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions,Keep all reagents on ice when not in storage

Lagerung: -20 °C

Informationen zur Lagerung: Some products may be shipped at room temperature. This will not affect their stability or performance. Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.

Haltbarkeit: 24 months

Referenzen für anti-IKZF1 Antikörper (ABIN2668828)

Yeung, Chung, Guess, Bell, Leinwand: "Myh7b/miR-499 gene expression is transcriptionally regulated by MRFs and Eos." in: Nucleic acids research, Vol. 40, Issue 15, pp. 7303-18, (2012) (PubMed).

Details zu IKZF1

Target: IKZF1 (IKAROS Family Zinc Finger 1 (Ikaros) (IKZF1))

Andere Bezeichnung: Ikaros

Hintergrund: Ikaros is a transcription factor that plays a critical role in the control of lymphohematopoiesis and immune regulation. All Ikaros isoforms share a common C-terminal domain that contains a transcription activation motif and two zinc finger motifs required for hetero- and homo-dimerization among the Ikaros isoforms, and for interactions with other proteins. Ikaros is abundantly expressed in pituitary mammosomatotrophs, where it deacetylates Histone H3 sites on the proximal growth hormone (GH) promoter to silence gene expression.

Molekulargewicht: 62 kDa

Gen-ID: 22778

NCBI Accession: NM_001025597

Pathways: Production of Molecular Mediator of Immune Response