IKZF1 Antikörper (Middle Region)
Kurzübersicht für IKZF1 Antikörper (Middle Region) (ABIN2777317)
Target
Alle IKZF1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- Middle Region
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Verwendungszweck
- IKZF1 Antibody - middle region
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Sequenz
- DLCKIGSERS LVLDRLASNV AKRKSSMPQK FLGDKGLSDT PYDSSASYEK
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Homologie
- Cow: 92%, Dog: 93%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 93%, Rabbit: 92%, Rat: 93%
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Produktmerkmale
- This is a rabbit polyclonal antibody against IKZF1. It was validated on Western Blot using a cell lysate as a positive control.
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Aufreinigung
- Affinity Purified
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Immunogen
- The immunogen is a synthetic peptide directed towards the middle region of human IKZF1
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Kommentare
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We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP31470-100UG
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 0.5 mg/mL
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Buffer
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- prevent freeze-thaw cycles
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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- IKZF1 (IKAROS Family Zinc Finger 1 (Ikaros) (IKZF1))
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Andere Bezeichnung
- IKZF1
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Hintergrund
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Background Information: IKZF1 binds and activates the enhancer (delta-A element) of the CD3-delta gene. It functions in the specification and the maturation of the T-lymphocyte. It also interacts with a critical control element in the TDT (terminal deoxynucleotidyltransferase) promoter as well as with the promoters for other genes expressed during early stages of B- and T-cell development.
Gene Name: IKAROS family zinc finger 1 (Ikaros)
Alternative Symbols: IK1, LYF1, LyF-1, CVID13, IKAROS, PPP1R92, PRO0758, ZNFN1A1, Hs.54452
Protein Name: DNA-binding protein Ikaros
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Molekulargewicht
- 57kDa
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Gen-ID
- 10320
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NCBI Accession
- NP_006051
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UniProt
- Q13422
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Pathways
- Production of Molecular Mediator of Immune Response
Target
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