HOXA5 Antikörper (Middle Region)

Produktnummer ABIN2777305

Zitiert in 2+ Publikationen. Der Kaninchen Polyklonal anti-HOXA5 Antikörper (ABIN2777305) detektiert spezifisch HOXA5 in WB und IHC. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Ratte, Maus, Schwein, Kaninchen, Rind (Kuh), Hund und Pferd.

Kurzübersicht für HOXA5 Antikörper (Middle Region) (ABIN2777305)

Target: HOXA5 (Homeobox A5 (HOXA5))

Reaktivität: Human, Ratte, Maus, Schwein, Kaninchen, Rind (Kuh), Hund, Pferd

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser HOXA5 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-HOXA5 Antikörper

Bindungsspezifität: Middle Region

Verwendungszweck: HOXA5 Antibody - middle region

Sequenz: VGTASGAEED APASSEQASA QSEPSPAPPA QPQIYPWMRK LHISHDNIGG

Homologie: Cow: 100%, Dog: 100%, Horse: 100%, Human: 100%, Mouse: 93%, Pig: 100%, Rabbit: 100%, Rat: 93%

Produktmerkmale: This is a rabbit polyclonal antibody against HOXA5. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human HOXA5

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP31447-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-HOXA5 Antikörper (ABIN2777305)

Heshmati, Kharazi, Türköz, Chang, Kamali Dolatabadi, Boström, Krstic, Boukoura, Wagner, Kadri, Månsson, Altun, Qian, Walfridsson: "The histone chaperone NAP1L3 is required for haematopoietic stem cell maintenance and differentiation." in: Scientific reports, Vol. 8, Issue 1, pp. 11202, (2019) (PubMed).

Boucherat, Montaron, Bérubé-Simard, Aubin, Philippidou, Wellik, Dasen, Jeannotte: "Partial functional redundancy between Hoxa5 and Hoxb5 paralog genes during lung morphogenesis." in: American journal of physiology. Lung cellular and molecular physiology, Vol. 304, Issue 12, pp. L817-30, (2013) (PubMed).

Details zu HOXA5

Target: HOXA5 (Homeobox A5 (HOXA5))

Andere Bezeichnung: HOXA5

Hintergrund:

Background Information: In vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named A, B, C, and D on four separate chromosomes. Expression of these proteins is spatially and temporally regulated during embryonic development. This gene is part of the A cluster on chromosome 7 and encodes a DNA-binding transcription factor which may regulate gene expression, morphogenesis, and differentiation. Methylation of this gene may result in the loss of its expression and, since the encoded protein upregulates the tumor suppressor p53, this protein may play an important role in tumorigenesis.

Gene Name: Homeobox A5

Alternative Symbols: HOX1, HOX1C, HOX1.3

Protein Name: HOXA5 protein EMBL CAG47073.1

Molekulargewicht: 29kDa

Gen-ID: 3202

NCBI Accession: NP_061975

UniProt: Q6FG31