ISL1 Antikörper (C-Term)

Produktnummer ABIN2777250

Produktdetails anti-ISL1 Antikörper

Target: ISL1 (ISL LIM Homeobox 1 (ISL1))

Bindungsspezifität: C-Term

Reaktivität: Human, Maus, Ratte, Zebrafisch (Danio rerio), Kaninchen, Rind (Kuh), Hund, Meerschweinchen, Schaf, Pferd

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ISL1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: IMMKQLQQQQ PNDKTNIQGM TGTPMVAASP ERHDGGLQAN PVEVQSYQPP

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%, Zebrafish: 93%

Produktmerkmale: This is a rabbit polyclonal antibody against ISL1. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human ISL1

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeat freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu ISL1

Target: ISL1 (ISL LIM Homeobox 1 (ISL1))

Andere Bezeichnung: ISL1 (ISL1 Produkte)

Synonyme: Xisl-1 antikoerper, Xislet-1 antikoerper, islet1 antikoerper, ISLET-1 antikoerper, ISLET1 antikoerper, Isl-1 antikoerper, islet-1 antikoerper, isl-1=homeobox antikoerper, Islet-1 antikoerper, ISL LIM homeobox 1 S homeolog antikoerper, ISL LIM homeobox 1 antikoerper, ISL1 transcription factor, LIM/homeodomain antikoerper, isl1.S antikoerper, ISL1 antikoerper, Isl1 antikoerper, isl1 antikoerper

Hintergrund: ISL1 is a member of the LIM/homeodomain family of transcription factors. It binds to the enhancer region of the insulin gene, among others, and may play an important role in regulating insulin gene expression. ISL1 is central to the development of pancreatic cell lineages and may also be required for motor neuron generation.
Alias Symbols: ISLET1, Isl-1
Protein Interaction Partner: ZNF511, KDM1A, RELA, SMAD3, CDKN2B, CDK6, APP, COPS5, SSBP4, LHX4, LDB2, ISL2, PECR, LDB1, LHX1, LHX3, LMX1A, RLIM, LMO2, ESR1, NR2F1, ISL1,
Protein Size: 349

Molekulargewicht: 39 kDa

Gen-ID: 3670

NCBI Accession: NM_002202, NP_002193

UniProt: P61371

Pathways: Positive Regulation of Peptide Hormone Secretion, Intracellular Steroid Hormone Receptor Signaling Pathway, Peptide Hormone Metabolism, Regulation of Intracellular Steroid Hormone Receptor Signaling, Nuclear Hormone Receptor Binding, Chromatin Binding