NFE2 Antikörper (N-Term)

Produktnummer ABIN2777230

Der Kaninchen Polyklonal anti-NFE2 Antikörper (ABIN2777230) detektiert spezifisch NFE2 in WB. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus, Ratte, Pferd, Rind (Kuh) und Meerschweinchen.

Kurzübersicht für NFE2 Antikörper (N-Term) (ABIN2777230)

Target: NFE2 (Nuclear Factor (Erythroid-Derived 2), 45kDa (NFE2))

Reaktivität: Human, Maus, Ratte, Pferd, Rind (Kuh), Meerschweinchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NFE2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-NFE2 Antikörper

Bindungsspezifität: N-Term

Verwendungszweck: NFE2 Antibody - N-terminal region

Sequenz: MSPCPPQQSR NRVIQLSTSE LGEMELTWQE IMSITELQGL NAPSEPSFEP

Homologie: Cow: 92%, Guinea Pig: 87%, Horse: 87%, Human: 100%, Mouse: 77%, Rat: 92%

Produktmerkmale: This is a rabbit polyclonal antibody against NFE2. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human NFE2

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP31217-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Details zu NFE2

Target: NFE2 (Nuclear Factor (Erythroid-Derived 2), 45kDa (NFE2))

Andere Bezeichnung: NFE2

Hintergrund:

Background Information: NFE2 is a component of the NF-E2 complex essential for regulating erythroid and megakaryocytic maturation and differentiation. NFE2 binds to the hypersensitive site 2 (HS2) of the beta-globin control region (LCR). This subunit (NFE2) recognizes the TCAT/C sequence of the AP-1-like core palindrome present in a number of erythroid and megakaryocytic gene promoters. NFE2 is requires MAFK or other small MAF proteins for binding to the NF-E2 motif. NFE2 may play a role in all aspects of hemoglobin production from globin and heme synthesis to procurement of iron.

Gene Name: Nuclear factor (erythroid-derived 2), 45 kDa

Alternative Symbols: p45, NF-E2

Protein Name: Transcription factor NF-E2 45 kDa subunit

Molekulargewicht: 41kDa

Gen-ID: 4778

NCBI Accession: NP_006154

UniProt: Q16621