NFE2 Antikörper (C-Term)

Produktnummer ABIN2777229

Der Kaninchen Polyklonal anti-NFE2 Antikörper wird verwendet zum Nachweis von NFE2 in Proben von Human, Maus, Ratte, Pferd, Rind (Kuh), Meerschweinchen, Hund und Kaninchen. Er wurde validiert für WB.

Kurzübersicht für NFE2 Antikörper (C-Term) (ABIN2777229)

Target: NFE2 (Nuclear Factor (Erythroid-Derived 2), 45kDa (NFE2))

Reaktivität: Human, Maus, Ratte, Pferd, Rind (Kuh), Meerschweinchen, Hund, Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NFE2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-NFE2 Antikörper

Bindungsspezifität: C-Term

Verwendungszweck: Nfe2 Antibody - C-terminal region

Sequenz: ARGEADRTLE VMRQQLAELY HDIFQHLRDE SGNSYSPEEY VLQQAADGAI

Homologie: Cow: 86%, Dog: 93%, Guinea Pig: 93%, Horse: 79%, Human: 100%, Mouse: 93%, Rabbit: 93%, Rat: 93%

Produktmerkmale: This is a rabbit polyclonal antibody against Nfe2. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of MOUSE Nfe2

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP31216-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Details zu NFE2

Target: NFE2 (Nuclear Factor (Erythroid-Derived 2), 45kDa (NFE2))

Andere Bezeichnung: Nfe2

Hintergrund:

Background Information: Nfe2 is a component of the NF-E2 complex essential for regulating erythroid and megakaryocytic maturation and differentiation.It binds to the hypersensitive site 2 (HS2) of the beta-globin control region (LCR). This subunit (NFE2) recognizes the TCAT/C sequence of the AP-1-like core palindrome present in a number of erythroid and megakaryocytic gene promoters. It requires MAFK or other small MAF proteins for binding to the NF-E2 motif. It may play a role in all aspects of hemoglobin production from globin and heme synthesis to procurement of iron.

Gene Name: nuclear factor (erythroid-derived 2), 45 kDa

Alternative Symbols: p4, p45, NF-E, NF-E2, p45NF, p45nf-, p45NFE2, p45nf-e2, NF-E2/P45

Protein Name: Transcription factor NF-E2 45 kDa subunit

Molekulargewicht: 41kDa

Gen-ID: 18022

NCBI Accession: NP_032711

UniProt: Q07279