NFE2 Antikörper (C-Term)

Produktnummer ABIN2777229

Der Kaninchen Polyklonal Anti-NFE2-Antikörper wurde für WB validiert. Er ist geeignet, NFE2 in Proben von Human, Maus, Ratte, Pferd, Rind (Kuh), Meerschweinchen, Hund und Kaninchen zu detektieren.

Kurzübersicht für NFE2 Antikörper (C-Term) (ABIN2777229)

Target: NFE2 (Nuclear Factor (Erythroid-Derived 2), 45kDa (NFE2))

Reaktivität: Human, Maus, Ratte, Pferd, Rind (Kuh), Meerschweinchen, Hund, Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NFE2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-NFE2 Antikörper

Bindungsspezifität: C-Term

Sequenz: ARGEADRTLE VMRQQLAELY HDIFQHLRDE SGNSYSPEEY VLQQAADGAI

Homologie: Cow: 86%, Dog: 93%, Guinea Pig: 93%, Horse: 79%, Human: 100%, Mouse: 93%, Rabbit: 93%, Rat: 93%

Produktmerkmale: This is a rabbit polyclonal antibody against Nfe2. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of MOUSE Nfe2

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeat freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu NFE2

Target: NFE2 (Nuclear Factor (Erythroid-Derived 2), 45kDa (NFE2))

Andere Bezeichnung: Nfe2

Hintergrund: Nfe2 is a component of the NF-E2 complex essential for regulating erythroid and megakaryocytic maturation and differentiation.It binds to the hypersensitive site 2 (HS2) of the beta-globin control region (LCR). This subunit (NFE2) recognizes the TCAT/C sequence of the AP-1-like core palindrome present in a number of erythroid and megakaryocytic gene promoters. It requires MAFK or other small MAF proteins for binding to the NF-E2 motif. It may play a role in all aspects of hemoglobin production from globin and heme synthesis to procurement of iron.
Alias Symbols: 45 kDa, NF-E2, p45, p45NFE2, p45nf-e2
Protein Interaction Partner: Psmd4, Kmt2d, Rbbp5, Wdr5, Ash2l, Men1, Mafk, H3f3a, Crebbp, Mapk8, Trip4, Plrg1, Pdlim4, Zfp292, Gtf2h2, Zscan2, Ubp1, Tsg101, Tial1, Supt4a, Snai1, Kdm5d, Kdm5c, Dpf2, Per1, Kat2b, Mybbp1a, Orc2, Ikbkg, Hoxb4, Hoxa4, Hcls1, Gtf2h1, Foxn2, E4f1, Dlx5, Ci
Protein Size: 373

Molekulargewicht: 41 kDa

Gen-ID: 18022

NCBI Accession: NM_008685, NP_032711

UniProt: Q07279