HNF1A Antikörper (C-Term)
Kurzübersicht für HNF1A Antikörper (C-Term) (ABIN2777209)
Target
Alle HNF1A Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- C-Term
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Sequenz
- QTMLITDTTN LSALASLTPT KQVFTSDTEA SSESGLHTPA SQATTLHVPS
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Homologie
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 85%, Rat: 100%
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Produktmerkmale
- This is a rabbit polyclonal antibody against HNF1A. It was validated on Western Blot.
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Aufreinigung
- Affinity Purified
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Immunogen
- The immunogen is a synthetic peptide directed towards the C-terminal region of human HNF1A
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 mg/mL
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid repeat freeze-thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- HNF1A (HNF1 Homeobox A (HNF1A))
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Andere Bezeichnung
- HNF1A
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Hintergrund
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The protein encoded by this gene is a transcription factor required for the expression of several liver-specific genes. The encoded protein functions as a homodimer and binds to the inverted palindrome 5'-GTTAATNATTAAC-3'. Defects in this gene are a cause of maturity onset diabetes of the young type 3 (MODY3) and also can result in the appearance of hepatic adenomas. Alternative splicing results in multiple transcript variants encoding different isoforms.
Alias Symbols: HNF1, LFB1, TCF1, MODY3, TCF-1, HNF-1A, IDDM20
Protein Size: 452 -
Molekulargewicht
- 49 kDa
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Gen-ID
- 6927
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NCBI Accession
- NM_000545, NP_000536
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UniProt
- P20823
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Pathways
- Hormone Transport, Carbohydrate Homeostasis
Target
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