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RUNX1 Antikörper (Middle Region)

RUNX1 Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Pferd, Kaninchen, Meerschweinchen WB, IHC Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN2777187
  • Target Alle RUNX1 Antikörper anzeigen
    RUNX1 (Runt-Related Transcription Factor 1 (RUNX1))
    Bindungsspezifität
    • 26
    • 16
    • 14
    • 13
    • 11
    • 11
    • 10
    • 7
    • 6
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region
    Reaktivität
    • 167
    • 103
    • 66
    • 12
    • 10
    • 9
    • 9
    • 9
    • 6
    • 5
    • 4
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Maus, Ratte, Rind (Kuh), Hund, Pferd, Kaninchen, Meerschweinchen
    Wirt
    • 163
    • 16
    • 2
    • 1
    Kaninchen
    Klonalität
    • 164
    • 19
    Polyklonal
    Konjugat
    • 104
    • 11
    • 7
    • 7
    • 7
    • 7
    • 7
    • 7
    • 6
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    Dieser RUNX1 Antikörper ist unkonjugiert
    Applikation
    • 137
    • 80
    • 46
    • 37
    • 32
    • 23
    • 15
    • 13
    • 13
    • 6
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    Sequenz
    ERSPPRILPP CTNASTGSAL LNPSLPNQSD VVEAEGSHSN SPTNMAPSAR
    Homologie
    Cow: 93%, Dog: 93%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 92%, Rabbit: 93%, Rat: 93%, Zebrafish: 77%
    Produktmerkmale
    This is a rabbit polyclonal antibody against RUNX1. It was validated on Western Blot using a cell lysate as a positive control.
    Aufreinigung
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the middle region of human RUNX1
    Top Product
    Discover our top product RUNX1 Primärantikörper
  • Applikationshinweise
    Optimal working dilutions should be determined experimentally by the investigator.
    Kommentare

    Antigen size: 453 AA

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freeze-thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Takeshita, Ichikawa, Nitta, Goyama, Asai, Ogawa, Chiba, Kurokawa: "AML1-Evi-1 specifically transforms hematopoietic stem cells through fusion of the entire Evi-1 sequence to AML1." in: Leukemia, Vol. 22, Issue 6, pp. 1241-9, (2008) (PubMed).

  • Target
    RUNX1 (Runt-Related Transcription Factor 1 (RUNX1))
    Andere Bezeichnung
    RUNX1 (RUNX1 Produkte)
    Synonyme
    RUNX1 antikoerper, runx1 antikoerper, AI462102 antikoerper, AML1 antikoerper, Cbfa2 antikoerper, Pebp2a2 antikoerper, Pebpa2b antikoerper, AML1-EVI-1 antikoerper, AMLCR1 antikoerper, CBFA2 antikoerper, EVI-1 antikoerper, PEBP2aB antikoerper, runxa antikoerper, Runx-1 antikoerper, XAML antikoerper, Xaml1 antikoerper, aml antikoerper, aml-1 antikoerper, aml1 antikoerper, aml1-evi-1 antikoerper, amlcr1 antikoerper, cbfa2 antikoerper, evi-1 antikoerper, pebp2ab antikoerper, Aml1 antikoerper, uncharacterized LOC473981 antikoerper, runt-related transcription factor antikoerper, runt related transcription factor 1 antikoerper, runt-related transcription factor 1 antikoerper, runt related transcription factor 1 L homeolog antikoerper, LOC473981 antikoerper, runt antikoerper, Runx1 antikoerper, RUNX1 antikoerper, runx1 antikoerper, runx1.L antikoerper
    Hintergrund
    Core binding factor (CBF) is a heterodimeric transcription factor that binds to the core element of many enhancers and promoters. RUNX1 is the alpha subunit of CBF and is thought to be involved in the development of normal hematopoiesis. Chromosomal trans
    Alias Symbols: AML1, AML1-EVI-1, AMLCR1, CBFA2, EVI-1, PEBP2aB
    Protein Interaction Partner: YAP1, UBC, HDAC11, SOX2, SMAD3, CTBP1, RUNX1, FOXP3, NCOR2, MYC, NOTCH1, UXT, CTBP2, KAT6A, PML, CREBBP, CBFB, PRMT1, HLA-DMA, HDAC2, HDAC1, CBFA2T3, RUNX1T1, CBFA2T2, ELAVL1, DNMT1, SPEN, RBM14, KMT2A, COPRS, HDAC3, TAL1, CDK1, SMARCC1, SMARCB1, SMARCA4,
    Protein Size: 453
    Molekulargewicht
    49 kDa
    Gen-ID
    861
    NCBI Accession
    NM_001001890, NP_001001890
    UniProt
    Q01196
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