Ret Proto-Oncogene Antikörper (C-Term)
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- Target Alle Ret Proto-Oncogene (RET) Antikörper anzeigen
- Ret Proto-Oncogene (RET)
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Bindungsspezifität
- C-Term
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Reaktivität
- Human, Maus, Ratte, Schwein, Kaninchen, Zebrafisch (Danio rerio), Rind (Kuh), Meerschweinchen, Pferd, Hund
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser Ret Proto-Oncogene Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Sequenz
- EMKLVHRDLA ARNILVAEGR KMKISDFGLS RDVYEEDSYV KRSQGRIPVK
- Homologie
- Cow: 100%, Dog: 100%, Guinea Pig: 90%, Horse: 100%, Human: 100%, Mouse: 90%, Pig: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%
- Produktmerkmale
- This is a rabbit polyclonal antibody against RET. It was validated on Western Blot.
- Aufreinigung
- Affinity Purified
- Top Product
- Discover our top product RET Primärantikörper
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- Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
- Kommentare
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Antigen size: 1114 AA
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- Ret Proto-Oncogene (RET)
- Andere Bezeichnung
- RET (RET Produkte)
- Synonyme
- c-ret antikoerper, cret antikoerper, etID315074.13 antikoerper, ret1 antikoerper, wu:fd13h01 antikoerper, X-ret antikoerper, ret-A antikoerper, xret antikoerper, RET antikoerper, MTC1 antikoerper, CDHF12 antikoerper, CDHR16 antikoerper, HSCR1 antikoerper, MEN2A antikoerper, MEN2B antikoerper, PTC antikoerper, RET-ELE1 antikoerper, RET51 antikoerper, RET9 antikoerper, c-Ret antikoerper, ret proto-oncogene receptor tyrosine kinase antikoerper, ret proto-oncogene S homeolog antikoerper, ret proto-oncogene antikoerper, ret antikoerper, ret.S antikoerper, RET antikoerper, Ret antikoerper
- Hintergrund
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This gene, a member of the cadherin superfamily, encodes one of the receptor tyrosine kinases, which are cell-surface molecules that transduce signals for cell growth and differentiation. This gene plays a crucial role in neural crest development, and it can undergo oncogenic activation in vivo and in vitro by cytogenetic rearrangement. Mutations in this gene are associated with the disorders multiple endocrine neoplasia, type IIA, multiple endocrine neoplasia, type IIB, Hirschsprung disease, and medullary thyroid carcinoma. Two transcript variants encoding different isoforms have been found for this gene. Additional transcript variants have been described but their biological validity has not been confirmed.
Alias Symbols: CDHF12, CDHR16, HSCR1, MEN2A, MEN2B, MTC1, PTC, RET-ELE1, RET51
Protein Interaction Partner: NOTCH2NL, UBC, CBLC, PDLIM7, HSP90AA1, GRB2, CBL, RET, MCRS1, IKBKG, DOK3, DOK5, DOK4, DOK6, SHC3, FRS2, DOK2, AKAP5, CBLB, GAB1, DOK1, NRTN, MAPK3, GRB10, GRB7, GFRA1, MAPK8, GDNF, PTK2, SHC1, MAPK14, SRC, MAPK1, PRKAR2A, PTPN11, PLCG1, PIK3R1, CRK, STAT
Protein Size: 1114 - Molekulargewicht
- 123 kDa
- Gen-ID
- 5979
- NCBI Accession
- NM_000323, NP_000314
- UniProt
- P07949
- Pathways
- RTK Signalweg, Dopaminergic Neurogenesis, Regulation of Cell Size, Tube Formation
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