TNNI1 Antikörper (Middle Region)
Kurzübersicht für TNNI1 Antikörper (Middle Region) (ABIN2777152)
Target
Alle TNNI1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- Middle Region
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Sequenz
- PPLRRVRVSA DAMLRALLGS KHKVSMDLRA NLKSVKKEDT EKERPVEVGD
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Homologie
- Cow: 100%, Dog: 100%, Goat: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%
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Produktmerkmale
- This is a rabbit polyclonal antibody against TNNI1. It was validated on Western Blot using a cell lysate as a positive control.
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Aufreinigung
- Protein A purified
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Immunogen
- The immunogen is a synthetic peptide directed towards the middle region of human TNNI1
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Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
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Kommentare
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Antigen size: 187 AA
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- Lot specific
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid repeated freeze-thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- TNNI1 (Slow Skeletal Troponin I (TNNI1))
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Andere Bezeichnung
- TNNI1
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Hintergrund
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Troponin proteins associate with tropomyosin and regulate the calcium sensitivity of the myofibril contractile apparatus of striated muscles. Each troponin-tropomyosin complex contains 1 Molecule from each of the 3 troponins: T, C, and I. The troponin I (TNI) subfamily contains three genes: TNI-skeletal-fast-twitch, TNI-skeletal-slow-twitch, and TNI-cardiac. TNNI1 prevents muscle contraction by inhibiting calcium-mediated conformational changes in actin-myosin complexes.
Alias Symbols: DKFZp451O223, SSTNI, TNN1
Protein Interaction Partner: PNMA1, MDFI, TRIM63, TRIM55, TNNC1, TNNT2, EIF3I, CCDC85B, TNNT1, ACTA1, PKD2L1,
Protein Size: 187 -
Molekulargewicht
- 21 kDa
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Gen-ID
- 7135
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NCBI Accession
- NM_003281, NP_003272
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UniProt
- P19237
Target
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