LEFTY2 Antikörper (N-Term)

Produktnummer ABIN2777146

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch LEFTY2 in WB und IHC. Es zeigt Reaktivität gegenüber Proben von Human, Maus, Ratte, Schwein, Rind (Kuh) und Pferd.

Kurzübersicht für LEFTY2 Antikörper (N-Term) (ABIN2777146)

Target: LEFTY2 (Left-Right Determination Factor 2 (LEFTY2))

Reaktivität: Human, Maus, Ratte, Schwein, Rind (Kuh), Pferd

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser LEFTY2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-LEFTY2 Antikörper

Bindungsspezifität: N-Term

Verwendungszweck: LEFTY2 Antibody - N-terminal region

Sequenz: MWPLWLCWAL WVLPLAGPGA ALTEEQLLGS LLRQLQLSEV PVLDRADMEK

Homologie: Cow: 79%, Horse: 93%, Human: 100%, Mouse: 79%, Pig: 86%, Rat: 83%

Produktmerkmale: This is a rabbit polyclonal antibody against LEFTY2. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human LEFTY2

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under ABIN8104203

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Details zu LEFTY2

Target: LEFTY2 (Left-Right Determination Factor 2 (LEFTY2))

Andere Bezeichnung: LEFTY2

Hintergrund:

Background Information: LEFTY2 is a member of the TGF-beta family of proteins. The protein is secreted and plays a role in left-right asymmetry determination of organ systems during development. The protein may also play a role in endometrial bleeding. Mutations in its gene have been associated with left-right axis malformations, particularly in the heart and lungs. Some types of infertility have been associated with dysregulated expression of its gene in the endometrium.This gene encodes a member of the TGF-beta family of proteins. The encoded protein is secreted and plays a role in left-right asymmetry determination of organ systems during development. The protein may also play a role in endometrial bleeding. Mutations in this gene have been associated with left-right axis malformations, particularly in the heart and lungs. Some types of infertility have been associated with dysregulated expression of this gene in the endometrium. Alternative processing of this protein can yield three different products. This gene is closely linked to both a related family member and a related pseudogene.

Gene Name: Left-right determination factor 2

Alternative Symbols: EBAF, LEFTA, TGFB4, LEFTYA

Protein Name: Left-right determination factor 2

Molekulargewicht: 40kDa

Gen-ID: 7044

NCBI Accession: NP_003231

UniProt: O00292