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FGF2 Antikörper (Middle Region)

Der Kaninchen Polyklonal Anti-FGF2-Antikörper wurde für WB und IHC validiert. Er ist geeignet, FGF2 in Proben von Human, Maus, Ratte, Kaninchen, Hund, Schaf, Rind (Kuh), Meerschweinchen, Zebrafisch (Danio rerio) und Pferd zu detektieren.
Produktnummer ABIN2777106

Kurzübersicht für FGF2 Antikörper (Middle Region) (ABIN2777106)

Target

Alle FGF2 Antikörper anzeigen
FGF2 (Fibroblast Growth Factor 2 (Basic) (FGF2))

Reaktivität

  • 137
  • 67
  • 60
  • 21
  • 17
  • 16
  • 7
  • 6
  • 5
  • 1
  • 1
  • 1
Human, Maus, Ratte, Kaninchen, Hund, Schaf, Rind (Kuh), Meerschweinchen, Zebrafisch (Danio rerio), Pferd

Wirt

  • 125
  • 44
  • 3
  • 1
  • 1
Kaninchen

Klonalität

  • 120
  • 54
Polyklonal

Konjugat

  • 91
  • 14
  • 12
  • 7
  • 6
  • 6
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
Dieser FGF2 Antikörper ist unkonjugiert

Applikation

  • 121
  • 63
  • 61
  • 38
  • 36
  • 36
  • 26
  • 26
  • 16
  • 15
  • 10
  • 8
  • 7
  • 6
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (IHC)
  • Bindungsspezifität

    • 36
    • 17
    • 16
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region

    Sequenz

    RLESNNYNTY RSRKYTSWYV ALKRTGQYKL GSKTGPGQKA ILFLPMSAKS

    Homologie

    Cow: 93%, Dog: 93%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 93%, Zebrafish: 86%

    Produktmerkmale

    This is a rabbit polyclonal antibody against FGF2. It was validated on Western Blot using a cell lysate as a positive control.

    Aufreinigung

    Affinity Purified

    Immunogen

    The immunogen is a synthetic peptide directed towards the middle region of human FGF2
  • Applikationshinweise

    Optimal working dilutions should be determined experimentally by the investigator.

    Kommentare

    Antigen size: 288 AA

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    Lot specific

    Buffer

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Handhabung

    Avoid repeated freeze-thaw cycles.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target

    FGF2 (Fibroblast Growth Factor 2 (Basic) (FGF2))

    Andere Bezeichnung

    FGF2

    Hintergrund

    The heparin-binding growth factors are angiogenic agents in vivo and are potent mitogens for a variety of cell types in vitro. There are differences in the tissue distribution and concentration of these 2 growth factors.The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members bind heparin and possess broad mitogenic and angiogenic activities. This protein has been implicated in diverse biological processes, such as limb and nervous system development, wound healing, and tumor growth. The mRNA for this gene contains multiple polyadenylation sites, and is alternatively translated from non-AUG (CUG) and AUG initiation codons, resulting in five different isoforms with distinct properties. The CUG-initiated isoforms are localized in the nucleus and are responsible for the intracrine effect, whereas, the AUG-initiated form is mostly cytosolic and is responsible for the paracrine and autocrine effects of this FGF. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
    Alias Symbols: BFGF, FGFB, HBGF-2
    Protein Interaction Partner: TUBG1, HMT1, PRMT1, CRYAB, THBS1, UBC, API5, CEP57, FGFRL1, FGFBP1, CXCL13, RPL6, RPS19, PTX3, NRP1, GPC4, RPS6KA3, GPC3, VTN, SDC3, SDC1, PF4, HSPG2, SDC2, FGFR1, FGFR4, FGFR3, FGF2, CSNK2A2, CSNK2B, CSNK2A1, CD44, SDC4,
    Protein Size: 288

    Molekulargewicht

    31 kDa

    Gen-ID

    2247

    NCBI Accession

    NM_002006, NP_001997

    UniProt

    P09038

    Pathways

    RTK Signalweg, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, C21-Steroid Hormone Metabolic Process, Inositol Metabolic Process, Glycosaminoglycan Metabolic Process, Protein targeting to Nucleus, S100 Proteine
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