BDNF Antikörper (N-Term)

Produktnummer ABIN2777092

Dieses Anti-BDNF-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von BDNF in WB. Geeignet für Human, Ratte, Maus, Schwein, Kaninchen, Hund und Zebrafisch (Danio rerio). Dieses Primary Antibody wurde in 1 Publikation zitiert.

Kurzübersicht für BDNF Antikörper (N-Term) (ABIN2777092)

Target: BDNF (Brain-Derived Neurotrophic Factor (BDNF))

Reaktivität: Human, Ratte, Maus, Schwein, Kaninchen, Hund, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser BDNF Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-BDNF Antikörper

Bindungsspezifität: N-Term

Sequenz: EELLDEDQKV RPNEENNKDA DLYTSRVMLS SQVPLEPPLL FLLEEYKNYL

Homologie: Dog: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against BDNF. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Human BDNF

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeat freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-BDNF Antikörper (ABIN2777092)

Galindo, Soslow, Brinkmeyer-Langford, Gupte, Smith, Sengsayadeth, Sawyer, Benson, Kornegay, Markham: "Translating golden retriever muscular dystrophy microarray findings to novel biomarkers for cardiac/skeletal muscle function in Duchenne muscular dystrophy." in: Pediatric research, Vol. 79, Issue 4, pp. 629-36, (2016) (PubMed).

Details zu BDNF

Target: BDNF (Brain-Derived Neurotrophic Factor (BDNF))

Andere Bezeichnung: BDNF

Hintergrund: The protein encoded by this gene is a member of the nerve growth factor family. It is induced by cortical neurons, and is necessary for survival of striatal neurons in the brain. Expression of this gene is reduced in both Alzheimer's and Huntington disease patients. This gene may play a role in the regulation of stress response and in the biology of mood disorders. Multiple transcript variants encoding distinct isoforms have been described for this gene.
Protein Interaction Partner: UBC, AGO3, INPP5K, F11R, JUNB, APP, ELAVL1, Ntrk2, CADPS2, MBTPS1, SORT1, NOS3, NTF4, NTF3, ESR1, NCAM1, CPE, BDNF,
Protein Size: 329

Molekulargewicht: 36 kDa

Gen-ID: 627

Pathways: RTK Signalweg, Synaptic Membrane, Feeding Behaviour, Dicarboxylic Acid Transport, Regulation of long-term Neuronal Synaptic Plasticity