Chromogranin A Antikörper (N-Term)

Produktnummer ABIN2777070

Der Kaninchen Polyklonal Anti-Chromogranin A-Antikörper wurde für WB validiert. Er ist geeignet, Chromogranin A in Proben von Human, Ratte, Maus, Schwein, Rind (Kuh), Pferd und Hund zu detektieren.

Kurzübersicht für Chromogranin A Antikörper (N-Term) (ABIN2777070)

Target: Chromogranin A (CHGA)

Reaktivität: Human, Ratte, Maus, Schwein, Rind (Kuh), Pferd, Hund

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Chromogranin A Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-Chromogranin A Antikörper

Bindungsspezifität: N-Term

Sequenz: PVSQECFETL RGDERILSIL RHQNLLKELQ DLALQGAKER AHQQKKHSGF

Homologie: Cow: 100%, Dog: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against CHGA. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human CHGA

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 457 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu Chromogranin A

Target: Chromogranin A (CHGA)

Andere Bezeichnung: CHGA

Hintergrund: CHGA is a member of the chromogranin/secretogranin family of neuroendocrine secretory proteins. It is found in secretory vesicles of neurons and endocrine cells. Its gene?s product is a precursor to three biologically active peptides, vasostatin, pancreastatin, and parastatin. These peptides act as autocrine or paracrine negative modulators of the neuroendocrine system. Other peptides, including chromostatin, beta-granin, WE-14 and GE-25, are also derived from the full-length protein. However, biological activities for these molecules have not been shown.The protein encoded by this gene is a member of the chromogranin/secretogranin family of neuroendocrine secretory proteins. It is found in secretory vesicles of neurons and endocrine cells. This gene product is a precursor to three biologically active peptides, vasostatin, pancreastatin, and parastatin. These peptides act as autocrine or paracrine negative modulators of the neuroendocrine system. Other peptides, including chromostatin, beta-granin, WE-14 and GE-25, are also derived from the full-length protein. However, biological activities for these molecules have not been shown.
Alias Symbols: CGA
Protein Interaction Partner: PARK2, UBC, CDC37, PFDN1, NEK2, SCG3, PLG,
Protein Size: 457

Molekulargewicht: 51 kDa

Gen-ID: 1113

NCBI Accession: NM_001275, NP_001266

UniProt: P10645

Pathways: Negative Regulation of Hormone Secretion, cAMP Metabolic Process, Regulation of G-Protein Coupled Receptor Protein Signaling