ALAS2 Antikörper (N-Term)

Produktnummer ABIN2777049

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch ALAS2 in WB und IHC. Er zeigt eine Reaktivität gegenüber Human, Maus, Ratte, Rind (Kuh), Kaninchen, Hund, Meerschweinchen und Pferd.

Kurzübersicht für ALAS2 Antikörper (N-Term) (ABIN2777049)

Target: ALAS2 (Aminolevulinate, delta-, Synthase 2 (ALAS2))

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Kaninchen, Hund, Meerschweinchen, Pferd

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ALAS2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-ALAS2 Antikörper

Bindungsspezifität: N-Term

Sequenz: VFKTVNRWAD AYPFAQHFSE ASVASKDVSV WCSNDYLGMS RHPQVLQATQ

Homologie: Cow: 86%, Dog: 93%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 93%, Rabbit: 93%, Rat: 93%

Produktmerkmale: This is a rabbit polyclonal antibody against ALAS2. It was validated on Western Blot and immunohistochemistry.

Aufreinigung: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human ALAS2

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 515 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu ALAS2

Target: ALAS2 (Aminolevulinate, delta-, Synthase 2 (ALAS2))

Andere Bezeichnung: ALAS2

Hintergrund: ALAS2 specifies an erythroid-specific mitochondrially located enzyme. The protein catalyzes the first step in the heme biosynthetic pathway. Defects in its gene cause X-linked pyridoxine-responsive sideroblastic anemia.The product of this gene specifies an erythroid-specific mitochondrially located enzyme. The encoded protein catalyzes the first step in the heme biosynthetic pathway. Defects in this gene cause X-linked pyridoxine-responsive sideroblastic anemia. Alternatively spliced transcript variants encoding different isoforms have been identified.
Alias Symbols: ANH1, ASB, PRO2399, XLSA, ALASE, XLDPP, XLEPP, ALAS-E
Protein Interaction Partner: BANP, GRB2, SUCLA2, RABGGTB,
Protein Size: 515

Molekulargewicht: 57 kDa

Gen-ID: 212

NCBI Accession: NM_001037969, NP_001033058

Pathways: Transition Metal Ion Homeostasis