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ALAS2 Antikörper (Center)

ALAS2 Reaktivität: Human, Maus WB Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN2854459
  • Target Alle ALAS2 Antikörper anzeigen
    ALAS2 (Aminolevulinate, delta-, Synthase 2 (ALAS2))
    Bindungsspezifität
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Center
    Reaktivität
    • 46
    • 35
    • 32
    • 7
    • 6
    • 5
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    Human, Maus
    Wirt
    • 37
    • 9
    Kaninchen
    Klonalität
    • 36
    • 10
    Polyklonal
    Konjugat
    • 21
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser ALAS2 Antikörper ist unkonjugiert
    Applikation
    • 34
    • 13
    • 9
    • 5
    • 4
    • 2
    • 1
    • 1
    Western Blotting (WB)
    Kreuzreaktivität
    Ratte (Rattus), Xenopus laevis, Zebrafisch (Danio rerio), Rind (Kuh), Xenopus tropicalis
    Kreuzreaktivität (Details)
    Rat (95 %), Xenopus laevis (81 %), Zebrafish (80 %), Bovine (95 %), Xenopus tropicalis (81 %)
    Produktmerkmale
    Rabbit Polyclonal antibody to ALAS-E (aminolevulinate, delta-, synthase 2)
    ALAS-E antibody [N3C3]
    Aufreinigung
    Purified by antigen-affinity chromatography.
    Immunogen
    Recombinant protein encompassing a sequence within the center region of human ALAS-E. The exact sequence is proprietary.
    Isotyp
    IgG
    Top Product
    Discover our top product ALAS2 Primärantikörper
  • Applikationshinweise
    Suggested dilution Reference Western blot 1:500-1:3000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceWestern blot1:500-1:3000*
    Kommentare

    Positive Control: Raji , K562 , HL60 , mouse liver

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 mg/mL
    Buffer
    0.1M Tris, 0.1M Glycine, 10 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.
    Konservierungsmittel
    Thimerosal (Merthiolate)
    Vorsichtsmaßnahmen
    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Vercellotti, Khan, Nguyen, Chen, Bruzzone, Bechtel, Brown, Nath, Steer, Hebbel, Belcher: "H-ferritin ferroxidase induces cytoprotective pathways and inhibits microvascular stasis in transgenic sickle mice." in: Frontiers in pharmacology, Vol. 5, pp. 79, (2014) (PubMed).

  • Target
    ALAS2 (Aminolevulinate, delta-, Synthase 2 (ALAS2))
    Andere Bezeichnung
    ALAS-E (ALAS2 Produkte)
    Synonyme
    anh1 antikoerper, asb antikoerper, xlsa antikoerper, ALAS-E antikoerper, ALASE antikoerper, ANH1 antikoerper, ASB antikoerper, XLDPP antikoerper, XLEPP antikoerper, XLSA antikoerper, alas-e antikoerper, cb1063 antikoerper, sau antikoerper, sauternes antikoerper, ALAS antikoerper, Alas-2 antikoerper, 5'-aminolevulinate synthase 2 antikoerper, aminolevulinate, delta-, synthase 2 antikoerper, aminolevulinic acid synthase 2, erythroid antikoerper, alas2 antikoerper, ALAS2 antikoerper, Alas2 antikoerper, alas2.L antikoerper
    Hintergrund
    The product of this gene specifies an erythroid-specific mitochondrially located enzyme. The encoded protein catalyzes the first step in the heme biosynthetic pathway. Defects in this gene cause X-linked pyridoxine-responsive sideroblastic anemia. Alternatively spliced transcript variants encoding different isoforms have been identified.

    Cellular Localization: Mitochondrion matrix
    Molekulargewicht
    65 kDa
    Gen-ID
    212
    Pathways
    Transition Metal Ion Homeostasis
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