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CES1 Antikörper (C-Term)

CES1 Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Meerschweinchen, Pferd, Kaninchen WB Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN2777043
  • Target Alle CES1 Antikörper anzeigen
    CES1 (Carboxylesterase 1 (CES1))
    Bindungsspezifität
    • 6
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reaktivität
    • 29
    • 15
    • 13
    • 5
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Maus, Ratte, Rind (Kuh), Hund, Meerschweinchen, Pferd, Kaninchen
    Wirt
    • 32
    • 4
    • 1
    • 1
    Kaninchen
    Klonalität
    • 35
    • 3
    Polyklonal
    Konjugat
    • 24
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser CES1 Antikörper ist unkonjugiert
    Applikation
    • 26
    • 11
    • 10
    • 6
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    Western Blotting (WB)
    Sequenz
    ANFARNGNPN GEGLPHWPEY NQKEGYLQIG ANTQAAQKLK DKEVAFWTNL
    Homologie
    Cow: 86%, Dog: 79%, Guinea Pig: 86%, Horse: 83%, Human: 100%, Mouse: 91%, Rabbit: 92%, Rat: 93%
    Produktmerkmale
    This is a rabbit polyclonal antibody against CES1. It was validated on Western Blot using a cell lysate as a positive control.
    Aufreinigung
    Protein A purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the C terminal region of human CES1
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    Discover our top product CES1 Primärantikörper
  • Applikationshinweise
    Optimal working dilutions should be determined experimentally by the investigator.
    Kommentare

    Antigen size: 567 AA

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freeze-thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    CES1 (Carboxylesterase 1 (CES1))
    Andere Bezeichnung
    CES1 (CES1 Produkte)
    Synonyme
    ACAT antikoerper, CE-1 antikoerper, CEH antikoerper, CES2 antikoerper, HMSE antikoerper, HMSE1 antikoerper, PCE-1 antikoerper, REH antikoerper, SES1 antikoerper, TGH antikoerper, hCE-1 antikoerper, CESDD1 antikoerper, CES1 antikoerper, CES-K1 antikoerper, APLE antikoerper, PMPMEase antikoerper, CES antikoerper, carboxylesterase 1 antikoerper, liver carboxylesterase 1 antikoerper, liver carboxylesterase antikoerper, carboxylesterase 1 (monocyte/macrophage serine esterase 1) antikoerper, CES1 antikoerper, CpipJ_CPIJ013026 antikoerper, CpipJ_CPIJ016339 antikoerper, LOC100009551 antikoerper, LOC454097 antikoerper, LOC699486 antikoerper, LOC100050915 antikoerper
    Hintergrund
    CES1 is one of the enzymes responsible for the hydrolysis of ester- and amide-bond-containing drugs such as cocaine and heroin. They also hydrolize long-chain fatty acid esters and thioesters. This enzyme is known to hydrolyze aromatic and aliphatic esters and is necessary for cellular cholesterol esterification. It may also play a role in detoxification in the lung and/or protection of the central nervous system from ester or amide compounds. Carboxylesterase deficiency may be associated with non-Hodgkin lymphoma or B-cell lymphocytic leukemia.Carboxylesterase 1 is a member of a large multigene family. The enzymes encoded by these genes are responsible for the hydrolysis of ester- and amide-bond-containing drugs such as cocaine and heroin. They also hydrolize long-chain fatty acid esters and thioesters. This enzyme is known to hydrolyze aromatic and aliphatic esters and is necessary for cellular cholesterol esterification. It may also play a role in detoxification in the lung and/or protection of the central nervous system from ester or amide compounds. Carboxylesterase deficiency may be associated with non-Hodgkin lymphoma or B-cell lymphocytic leukemia. Three transcript variants encoding three different isoforms have been found for this gene.
    Alias Symbols: CEH, CES2, HMSE, HMSE1, SES1, REH, TGH, ACAT, PCE-1
    Protein Interaction Partner: BMPR2, GUSB, CES1,
    Protein Size: 567
    Molekulargewicht
    62 kDa
    Gen-ID
    1066
    NCBI Accession
    NM_001025194, NP_001020365
    UniProt
    P23141
    Pathways
    Monocarboxylic Acid Catabolic Process
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