CES1 Antikörper (C-Term)

Produktnummer ABIN2777043

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch CES1 in WB. Er zeigt eine Reaktivität gegenüber Human, Maus, Ratte, Rind (Kuh), Hund, Meerschweinchen, Pferd und Kaninchen.

Kurzübersicht für CES1 Antikörper (C-Term) (ABIN2777043)

Target: CES1 (Carboxylesterase 1 (CES1))

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Meerschweinchen, Pferd, Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CES1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-CES1 Antikörper

Bindungsspezifität: C-Term

Sequenz: ANFARNGNPN GEGLPHWPEY NQKEGYLQIG ANTQAAQKLK DKEVAFWTNL

Homologie: Cow: 86%, Dog: 79%, Guinea Pig: 86%, Horse: 83%, Human: 100%, Mouse: 91%, Rabbit: 92%, Rat: 93%

Produktmerkmale: This is a rabbit polyclonal antibody against CES1. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human CES1

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 567 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu CES1

Target: CES1 (Carboxylesterase 1 (CES1))

Andere Bezeichnung: CES1

Hintergrund: CES1 is one of the enzymes responsible for the hydrolysis of ester- and amide-bond-containing drugs such as cocaine and heroin. They also hydrolize long-chain fatty acid esters and thioesters. This enzyme is known to hydrolyze aromatic and aliphatic esters and is necessary for cellular cholesterol esterification. It may also play a role in detoxification in the lung and/or protection of the central nervous system from ester or amide compounds. Carboxylesterase deficiency may be associated with non-Hodgkin lymphoma or B-cell lymphocytic leukemia.Carboxylesterase 1 is a member of a large multigene family. The enzymes encoded by these genes are responsible for the hydrolysis of ester- and amide-bond-containing drugs such as cocaine and heroin. They also hydrolize long-chain fatty acid esters and thioesters. This enzyme is known to hydrolyze aromatic and aliphatic esters and is necessary for cellular cholesterol esterification. It may also play a role in detoxification in the lung and/or protection of the central nervous system from ester or amide compounds. Carboxylesterase deficiency may be associated with non-Hodgkin lymphoma or B-cell lymphocytic leukemia. Three transcript variants encoding three different isoforms have been found for this gene.
Alias Symbols: CEH, CES2, HMSE, HMSE1, SES1, REH, TGH, ACAT, PCE-1
Protein Interaction Partner: BMPR2, GUSB, CES1,
Protein Size: 567

Molekulargewicht: 62 kDa

Gen-ID: 1066

NCBI Accession: NM_001025194, NP_001020365

UniProt: P23141

Pathways: Monocarboxylic Acid Catabolic Process