OXT Antikörper (N-Term)

Produktnummer ABIN2777015

Produktdetails anti-OXT Antikörper

Target: OXT (Oxytocin, Prepropeptide (OXT))

Bindungsspezifität: N-Term

Reaktivität: Human, Ratte, Maus, Schaf, Rind (Kuh), Hund, Meerschweinchen, Pferd, Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser OXT Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: LGLLALTSAC YIQNCPLGGK RAAPDLDVRK CLPCGPGGKG RCFGPNICCA

Homologie: Cow: 85%, Dog: 92%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 79%, Rabbit: 86%, Rat: 93%, Sheep: 85%

Produktmerkmale: This is a rabbit polyclonal antibody against OXT. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 125 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu OXT

Target: OXT (Oxytocin, Prepropeptide (OXT))

Andere Bezeichnung: OXT (OXT Produkte)

Synonyme: OT antikoerper, OT-NPI antikoerper, OXT-NPI antikoerper, Oxy antikoerper, OTNPI antikoerper, NEURL1 antikoerper, RNF67 antikoerper, bA416N2.1 antikoerper, neu antikoerper, neu-1 antikoerper, Ocytocin antikoerper, Oxytocin antikoerper, oxytocin/neurophysin I prepropeptide antikoerper, oxytocin antikoerper, oxytocin/neurophysin 1 prepropeptide antikoerper, neuralized E3 ubiquitin protein ligase 1 antikoerper, vasopressin-neurophysin 2 antikoerper, OXT antikoerper, Oxt antikoerper, NEURL1 antikoerper, LOC100066842 antikoerper

Hintergrund: There are two proteins encoded by this gene, oxytocin and neurophysin I. Oxytocin is posterior pituitary hormone which is synthesized as an inactive precursor in the hypothalamus along with its carrier protein neurophysin I. Together with neurophysin, it is packaged into neurosecretory vesicles and transported axonally to the nerve endings in the neurohypophysis, where it is either stored or secreted into the bloodstream. The precursor seems to be activated while it is being transported along the axon to the posterior pituitary. This hormone contracts smooth muscle during parturition and lactation. It is also involved in cognition, tolerance, adaptation and complex sexual and maternal behaviour, as well as in the regulation of water excretion and cardiovascular functions.
Alias Symbols: MGC126890, MGC126892, OT, OT-NPI
Protein Interaction Partner: TXNDC17, ESR2, PREP, OXTR, KMT2A,
Protein Size: 125

Molekulargewicht: 9 kDa

Gen-ID: 5020

NCBI Accession: NM_000915, NP_000906

UniProt: P01178

Pathways: Myometrial Relaxation and Contraction, Feeding Behaviour