OXT Antikörper (N-Term)

Produktnummer ABIN2777015

Der Kaninchen Polyklonal anti-OXT Antikörper (ABIN2777015) detektiert spezifisch OXT in WB. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Ratte, Maus, Rind (Kuh), Hund, Meerschweinchen, Pferd, Kaninchen und Schaf.

Kurzübersicht für OXT Antikörper (N-Term) (ABIN2777015)

Target: OXT (Oxytocin, Prepropeptide (OXT))

Reaktivität: Human, Ratte, Maus, Rind (Kuh), Hund, Meerschweinchen, Pferd, Kaninchen, Schaf

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser OXT Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-OXT Antikörper

Bindungsspezifität: N-Term

Verwendungszweck: OXT Antibody - N-terminal region

Sequenz: LGLLALTSAC YIQNCPLGGK RAAPDLDVRK CLPCGPGGKG RCFGPNICCA

Homologie: Cow: 85%, Dog: 92%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 79%, Rabbit: 86%, Rat: 93%, Sheep: 85%

Produktmerkmale: This is a rabbit polyclonal antibody against OXT. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP41829-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Details zu OXT

Target: OXT (Oxytocin, Prepropeptide (OXT))

Andere Bezeichnung: OXT

Hintergrund:

Background Information: There are two proteins encoded by this gene, oxytocin and neurophysin I. Oxytocin is posterior pituitary hormone which is synthesized as an inactive precursor in the hypothalamus along with its carrier protein neurophysin I. Together with neurophysin, it is packaged into neurosecretory vesicles and transported axonally to the nerve endings in the neurohypophysis, where it is either stored or secreted into the bloodstream. The precursor seems to be activated while it is being transported along the axon to the posterior pituitary. This hormone contracts smooth muscle during parturition and lactation. It is also involved in cognition, tolerance, adaptation and complex sexual and maternal behaviour, as well as in the regulation of water excretion and cardiovascular functions.

Gene Name: Oxytocin, prepropeptide

Alternative Symbols: OT, OT-NPI, OXT-NPI

Protein Name: Oxytocin-neurophysin 1

Molekulargewicht: 9kDa

Gen-ID: 5020

NCBI Accession: NP_000906

UniProt: P01178

Pathways: Myometrial Relaxation and Contraction, Feeding Behaviour