OXT Antikörper (Internal Region)

Produktnummer ABIN7222882

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch OXT in WB, ELISA, IHC und IF. Es zeigt Reaktivität gegenüber Proben von Human und Ratte.

Kurzübersicht für OXT Antikörper (Internal Region) (ABIN7222882)

Target: OXT (Oxytocin, Prepropeptide (OXT))

Reaktivität: Human, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser OXT Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Produktdetails anti-OXT Antikörper

Bindungsspezifität: Internal Region

Verwendungszweck: Rabbit Anti-Neurophysin I Polyclonal Antibody

Spezifität: Neurophysin I Polyclonal Antibody detects endogenous levels of Neurophysin I protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the Internal region of human Neurophysin I

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,IHC 1:100-1:300,ELISA 1:20000,IF 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu OXT

Target: OXT (Oxytocin, Prepropeptide (OXT))

Andere Bezeichnung: Neurophysin I

Hintergrund: OXT, OT, Oxytocin-neurophysin 1, OT-NPIOXT encodes a precursor protein that is processed to produce oxytocin and neurophysin I. Oxytocin is a posterior pituitary hormone which is synthesized as an inactive precursor in the hypothalamus along with its carrier protein neurophysin I. Together with neurophysin, it is packaged into neurosecretory vesicles and transported axonally to the nerve endings in the neurohypophysis, where it is either stored or secreted into the bloodstream. The precursor seems to be activated while it is being transported along the axon to the posterior pituitary. This hormone contracts smooth muscle during parturition and lactation. It is also involved in cognition, tolerance, adaptation and complex sexual and maternal behaviour, as well as in the regulation of water excretion and cardiovascular functions.

Molekulargewicht: 19kD

Gen-ID: 5020

UniProt: P01178

Pathways: Myometrial Relaxation and Contraction, Feeding Behaviour