NPY1R Antikörper (Middle Region)

Produktnummer ABIN2777014

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch NPY1R in WB und IHC. Er zeigt eine Reaktivität gegenüber Human, Maus, Ratte, Pferd, Hund, Meerschweinchen, Kaninchen, Rind (Kuh) und Schaf.

Kurzübersicht für NPY1R Antikörper (Middle Region) (ABIN2777014)

Target: NPY1R (Neuropeptide Y Receptor Y1 (NPY1R))

Reaktivität: Human, Maus, Ratte, Pferd, Hund, Meerschweinchen, Kaninchen, Rind (Kuh), Schaf

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NPY1R Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-NPY1R Antikörper

Bindungsspezifität: Middle Region

Sequenz: TDEPFQNVTL DAYKDKYVCF DQFPSDSHRL SYTTLLLVLQ YFGPLCFIFI

Homologie: Cow: 93%, Dog: 93%, Guinea Pig: 93%, Horse: 79%, Human: 100%, Mouse: 79%, Rabbit: 93%, Rat: 93%, Sheep: 93%

Produktmerkmale: This is a rabbit polyclonal antibody against NPY1R. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human NPY1R

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 384 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu NPY1R

Target: NPY1R (Neuropeptide Y Receptor Y1 (NPY1R))

Andere Bezeichnung: NPY1R

Hintergrund: Neuropeptide Y (NPY) is one of the most abundant neuropeptides in the mammalian nervous system and exhibits a diverse range of important physiologic activities, including effects on psychomotor activity, food intake, regulation of central endocrine secretion, and potent vasoactive effects on the cardiovascular system. Two major subtypes of NPY (Y1 and Y2) have been defined by pharmacologic criteria. NPY receptors, such as NPY1R, have been identified in a variety of tissues, including brain, spleen, small intestine, kidney, testis, placenta, and aortic smooth muscle.Neuropeptide Y (NPY, MIM 162640) is one of the most abundant neuropeptides in the mammalian nervous system and exhibits a diverse range of important physiologic activities, including effects on psychomotor activity, food intake, regulation of central endocrine secretion, and potent vasoactive effects on the cardiovascular system. Two major subtypes of NPY (Y1 and Y2) have been defined by pharmacologic criteria. NPY receptors, such as NPY1R, have been identified in a variety of tissues, including brain, spleen, small intestine, kidney, testis, placenta, and aortic smooth muscle (Herzog et al., 1992 [PubMed 1321422]).[supplied by OMIM]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: NPYR, NPY1-R
Protein Interaction Partner: ATP13A2, LSM7, PYY, NPY,
Protein Size: 384

Molekulargewicht: 44 kDa

Gen-ID: 4886

NCBI Accession: NM_000909, NP_000900

UniProt: P25929

Pathways: Negative Regulation of Hormone Secretion, Feeding Behaviour