GSTM2 Antikörper (N-Term)

Produktnummer ABIN2777010

Der Kaninchen Polyklonal Anti-GSTM2-Antikörper wurde für WB und IHC validiert. Er ist geeignet, GSTM2 in Proben von Human und Zebrafisch (Danio rerio) zu detektieren.

Kurzübersicht für GSTM2 Antikörper (N-Term) (ABIN2777010)

Target: GSTM2 (Glutathione S-Transferase mu 2 (Muscle) (GSTM2))

Reaktivität: Human, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GSTM2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-GSTM2 Antikörper

Bindungsspezifität: N-Term

Sequenz: TQSNAILRYI ARKHNLCGES EKEQIREDIL ENQFMDSRMQ LAKLCYDPDF

Homologie: Human: 100%, Zebrafish: 79%

Produktmerkmale: This is a rabbit polyclonal antibody against GSTM2. It was validated on Western Blot and immunohistochemistry.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human GSTM2

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

Antigen size: 218 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu GSTM2

Target: GSTM2 (Glutathione S-Transferase mu 2 (Muscle) (GSTM2))

Andere Bezeichnung: GSTM2

Hintergrund: At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. GSTM2 is a glutathione S-transferase that belongs to the mu class. The mu class of enzymes functions in the detoxification of electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins and products of oxidative stress, by conjugation with glutathione.Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. This gene encodes a glutathione S-transferase that belongs to the mu class. The mu class of enzymes functions in the detoxification of electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins and products of oxidative stress, by conjugation with glutathione. The genes encoding the mu class of enzymes are organized in a gene cluster on chromosome 1p13.3 and are known to be highly polymorphic. These genetic variations can change an individual's susceptibility to carcinogens and toxins as well as affect the toxicity and efficacy of certain drugs.
Alias Symbols: GST4, GSTM, GSTM2-2, GTHMUS, MGC117303
Protein Interaction Partner: UBC, GSTM3, GSTM2, GSTM1,
Protein Size: 218

Molekulargewicht: 26 kDa

Gen-ID: 2946

NCBI Accession: NM_000848, NP_000839

UniProt: P28161

Pathways: Negative Regulation of Transporter Activity