LCAT Antikörper (N-Term)

Produktnummer ABIN2776941

Zitiert in 1 Publikation. Der Kaninchen Polyklonal anti-LCAT Antikörper (ABIN2776941) detektiert spezifisch LCAT in WB. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Ratte, Maus, Hund, Rind (Kuh), Meerschweinchen, Pferd, Kaninchen und Schaf.

Kurzübersicht für LCAT Antikörper (N-Term) (ABIN2776941)

Target: LCAT (Lecithin-Cholesterol Acyltransferase (LCAT))

Reaktivität: Human, Ratte, Maus, Hund, Rind (Kuh), Meerschweinchen, Pferd, Kaninchen, Schaf

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser LCAT Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-LCAT Antikörper

Bindungsspezifität: N-Term

Verwendungszweck: LCAT Antibody - N-terminal region

Sequenz: MGPPGSPWQW VTLLLGLLLP PAAPFWLLNV LFPPHTTPKA ELSNHTRPVI

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against LCAT. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human LCAT

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP41695-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1.0 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-LCAT Antikörper (ABIN2776941)

Hirata, Yimin, Segawa, Ozaki, Kobayashi, Shigyo, Chiba: "Xanthohumol prevents atherosclerosis by reducing arterial cholesterol content via CETP and apolipoprotein E in CETP-transgenic mice." in: PLoS ONE, Vol. 7, Issue 11, pp. e49415, (2012) (PubMed).

Details zu LCAT

Target: LCAT (Lecithin-Cholesterol Acyltransferase (LCAT))

Andere Bezeichnung: LCAT

Hintergrund:

Background Information: LCAT is an extracellular cholesterol esterifying enzyme, lecithin-cholesterol acyltransferase. The esterification of cholesterol is required for cholesterol transport. Mutations in its gene have been found to cause fish-eye disease as well as LCAT deficiency.This gene encodes the extracellular cholesterol esterifying enzyme, lecithin-cholesterol acyltransferase. The esterification of cholesterol is required for cholesterol transport. Mutations in this gene have been found to cause fish-eye disease as well as LCAT deficiency.

Gene Name: Lecithin-cholesterol acyltransferase

Protein Name: Phosphatidylcholine-sterol acyltransferase

Molekulargewicht: 48kDa

Gen-ID: 3931

NCBI Accession: NP_000220

UniProt: P04180

Pathways: Lipid Metabolism