Complement C2 Antikörper (Middle Region)

Produktnummer ABIN2776930

Der Kaninchen Polyklonal anti-Complement C2 Antikörper wird verwendet zum Nachweis von Complement C2 in Proben von Human, Ratte, Maus, Hund, Pferd, Schwein, Rind (Kuh), Kaninchen und Schaf. Er wurde validiert für WB.

Kurzübersicht für Complement C2 Antikörper (Middle Region) (ABIN2776930)

Target: Complement C2

Reaktivität: Human, Ratte, Maus, Hund, Pferd, Schwein, Rind (Kuh), Kaninchen, Schaf

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Complement C2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-Complement C2 Antikörper

Bindungsspezifität: Middle Region

Verwendungszweck: C2 Antibody - middle region

Sequenz: INQKRNDYLD IYAIGVGKLD VDWRELNELG SKKDGERHAF ILQDTKALHQ

Homologie: Cow: 93%, Dog: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 93%, Rat: 100%, Sheep: 93%

Produktmerkmale: This is a rabbit polyclonal antibody against C2. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human C2

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under ABIN8097850

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1.0 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Details zu Complement C2

Target: Complement C2

Andere Bezeichnung: C2

Hintergrund:

Background Information: Component C2 is a serum glycoprotein that functions as part of the classical pathway of the complement system. Activated C1 cleaves C2 into C2a and C2b. The serine proteinase C2a then combines with complement factor 4b to create the C3 or C5 convertase. Deficiency of C2 has been reported to associated with certain autoimmune diseases and SNPs in this gene have been associated with altered susceptibility to age-related macular degeneration. This gene localizes within the class III region of the MHC on the short arm of chromosome 6. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional transcript variants have been described in publications but their full-length sequence has not been determined.

Gene Name: complement C2

Alternative Symbols: CO2, ARMD14

Protein Name: complement C2

Molekulargewicht: 83kDa

Gen-ID: 717

NCBI Accession: NP_000054

UniProt: P06681