MASP2 Antikörper (Middle Region)

Produktnummer ABIN2776886

Produktdetails anti-MASP2 Antikörper

Target: MASP2 (Mannan-Binding Lectin serine Peptidase 2 (MASP2))

Bindungsspezifität: Middle Region

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Schwein

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MASP2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: YPQPYPKLSS CTYSIRLEDG FSVILDFVES FDVETHPEAQ CPYDSLKIQT

Homologie: Cow: 100%, Guinea Pig: 79%, Horse: 77%, Human: 100%, Mouse: 100%, Pig: 93%, Rat: 92%, Zebrafish: 77%

Produktmerkmale: This is a rabbit polyclonal antibody against Masp2. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide corresponding to a region of Mouse

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 685 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu MASP2

Target: MASP2 (Mannan-Binding Lectin serine Peptidase 2 (MASP2))

Andere Bezeichnung: Masp2 (MASP2 Produkte)

Synonyme: MAP19 antikoerper, MASP-2 antikoerper, MASP1P1 antikoerper, sMAP antikoerper, MAp19 antikoerper, mannan binding lectin serine peptidase 2 antikoerper, mannan-binding lectin serine peptidase 2 antikoerper, MASP2 antikoerper, Masp2 antikoerper

Hintergrund: Masp2 is a serum protease that plays an important role in the activation of the complement system via mannose-binding lectin. After activation by auto-catalytic cleavage it cleaves C2 and C4, leading to their activation and to the formation of C3 convertase.
Alias Symbols: MASP-2, MAp19
Protein Size: 685

Molekulargewicht: 75 kDa

Gen-ID: 17175

NCBI Accession: NM_001003893, NP_001003893

UniProt: Q91WP0

Pathways: Komplementsystem