CKMT2 Antikörper (C-Term)

Produktnummer ABIN2776840

Dieses Anti-CKMT2-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von CKMT2 in WB. Geeignet für Human, Maus, Ratte, Hund, Kaninchen, Rind (Kuh), Pferd, Zebrafisch (Danio rerio), Meerschweinchen und Saccharomyces cerevisiae.

Kurzübersicht für CKMT2 Antikörper (C-Term) (ABIN2776840)

Target: CKMT2 (Creatine Kinase, Mitochondrial 2 (Sarcomeric) (CKMT2))

Reaktivität: Human, Maus, Ratte, Hund, Kaninchen, Rind (Kuh), Pferd, Zebrafisch (Danio rerio), Meerschweinchen, Saccharomyces cerevisiae

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CKMT2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-CKMT2 Antikörper

Bindungsspezifität: C-Term

Sequenz: ISNIDRIGRS EVELVQIVID GVNYLVDCEK KLERGQDIKV PPPLPQFGKK

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Yeast: 80%, Zebrafish: 83%

Produktmerkmale: This is a rabbit polyclonal antibody against CKMT2. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human CKMT2

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 419 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu CKMT2

Target: CKMT2 (Creatine Kinase, Mitochondrial 2 (Sarcomeric) (CKMT2))

Andere Bezeichnung: CKMT2

Hintergrund: Mitochondrial creatine kinase (MtCK) is responsible for the transfer of high energy phosphate from mitochondria to the cytosolic carrier, creatine. It belongs to the creatine kinase isoenzyme family. It exists as two isoenzymes, sarcomeric MtCK and ubiquitous MtCK, encoded by separate genes. Mitochondrial creatine kinase occurs in two different oligomeric forms: dimers and octamers, in contrast to the exclusively dimeric cytosolic creatine kinase isoenzymes. Sarcomeric mitochondrial creatine kinase has 80 % homology with the coding exons of ubiquitous mitochondrial creatine kinase. This gene contains sequences homologous to several motifs that are shared among some nuclear genes encoding mitochondrial proteins and thus may be essential for the coordinated activation of these genes during mitochondrial biogenesis. Three transcript variants encoding the same protein have been found for this gene.Mitochondrial creatine kinase (MtCK) is responsible for the transfer of high energy phosphate from mitochondria to the cytosolic carrier, creatine. It belongs to the creatine kinase isoenzyme family. It exists as two isoenzymes, sarcomeric MtCK and ubiquitous MtCK, encoded by separate genes. Mitochondrial creatine kinase occurs in two different oligomeric forms: dimers and octamers, in contrast to the exclusively dimeric cytosolic creatine kinase isoenzymes. Sarcomeric mitochondrial creatine kinase has 80 % homology with the coding exons of ubiquitous mitochondrial creatine kinase. This gene contains sequences homologous to several motifs that are shared among some nuclear genes encoding mitochondrial proteins and thus may be essential for the coordinated activation of these genes during mitochondrial biogenesis. Three transcript variants encoding the same protein have been found for this gene.
Alias Symbols: SMTCK
Protein Interaction Partner: UBC, ABHD6, TMED9, ELN, PSMD4, LRIF1, OLFML3, UNC119, CKMT2,
Protein Size: 419

Molekulargewicht: 43 kDa

Gen-ID: 1160

NCBI Accession: NM_001825, NP_001816

UniProt: P17540