CKMT2 Antikörper (N-Term)

Produktnummer ABIN2776839

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch CKMT2 in WB und IHC. Er zeigt eine Reaktivität gegenüber Human, Maus, Ratte, Hund, Schwein, Kaninchen, Rind (Kuh), Pferd, Zebrafisch (Danio rerio) und Meerschweinchen und wurde in 2+ Publikationen erwähnt.

Kurzübersicht für CKMT2 Antikörper (N-Term) (ABIN2776839)

Target: CKMT2 (Creatine Kinase, Mitochondrial 2 (Sarcomeric) (CKMT2))

Reaktivität: Human, Maus, Ratte, Hund, Schwein, Kaninchen, Rind (Kuh), Pferd, Zebrafisch (Danio rerio), Meerschweinchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CKMT2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-CKMT2 Antikörper

Bindungsspezifität: N-Term

Sequenz: GTSVLTTGYL LNRQKVCAEV REQPRLFPPS ADYPDLRKHN NCMAECLTPA

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 86%

Produktmerkmale: This is a rabbit polyclonal antibody against CKMT2. It was validated on Western Blot and immunohistochemistry.

Aufreinigung: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human CKMT2

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 419 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-CKMT2 Antikörper (ABIN2776839)

Choudhuri, Maitra, Evans: "Translation initiation factor eIF3h targets specific transcripts to polysomes during embryogenesis." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 110, Issue 24, pp. 9818-23, (2013) (PubMed).

Guerrero, Wuyam, Mezin, Vivodtzev, Vendelin, Borel, Hacini, Chavanon, Imbeaud, Saks, Pison: "Functional coupling of adenine nucleotide translocase and mitochondrial creatine kinase is enhanced after exercise training in lung transplant skeletal muscle." in: American journal of physiology. Regulatory, integrative and comparative physiology, Vol. 289, Issue 4, pp. R1144-54, (2005) (PubMed).

Details zu CKMT2

Target: CKMT2 (Creatine Kinase, Mitochondrial 2 (Sarcomeric) (CKMT2))

Andere Bezeichnung: CKMT2

Hintergrund: Mitochondrial creatine kinase (MtCK) is responsible for the transfer of high energy phosphate from mitochondria to the cytosolic carrier, creatine. It belongs to the creatine kinase isoenzyme family. It exists as two isoenzymes, sarcomeric MtCK and ubiquitous MtCK, encoded by separate genes. Mitochondrial creatine kinase occurs in two different oligomeric forms: dimers and octamers, in contrast to the exclusively dimeric cytosolic creatine kinase isoenzymes. Sarcomeric mitochondrial creatine kinase has 80 % homology with the coding exons of ubiquitous mitochondrial creatine kinase.Mitochondrial creatine kinase (MtCK) is responsible for the transfer of high energy phosphate from mitochondria to the cytosolic carrier, creatine. It belongs to the creatine kinase isoenzyme family. It exists as two isoenzymes, sarcomeric MtCK and ubiquitous MtCK, encoded by separate genes. Mitochondrial creatine kinase occurs in two different oligomeric forms: dimers and octamers, in contrast to the exclusively dimeric cytosolic creatine kinase isoenzymes. Sarcomeric mitochondrial creatine kinase has 80 % homology with the coding exons of ubiquitous mitochondrial creatine kinase. This gene contains sequences homologous to several motifs that are shared among some nuclear genes encoding mitochondrial proteins and thus may be essential for the coordinated activation of these genes during mitochondrial biogenesis.
Alias Symbols: SMTCK
Protein Interaction Partner: UBC, ABHD6, TMED9, ELN, PSMD4, LRIF1, OLFML3, UNC119, CKMT2,
Protein Size: 419

Molekulargewicht: 46 kDa

Gen-ID: 1160

NCBI Accession: NM_001825, NP_001816

UniProt: P17540