PLA2G5 Antikörper (phospholipase A2, Group V) (Middle Region)

Details for Product anti-PLA2G5 Antibody No. ABIN2776806, Anbieter: Anmelden zum Anzeigen
Antigen
  • PLA2
  • sPLA2
  • FRFB
  • GV-PLA2
  • PLA2-10
  • hVPLA(2)
  • phospholipase A2 group V
  • phospholipase A2, group V
  • PLA2G5
  • Pla2g5
Epitop
Middle Region
13
10
8
8
3
1
1
Reaktivität
Rind (Kuh), Hund, Meerschweinchen, Pferd, Human, Ratte (Rattus)
33
15
12
2
1
1
1
Wirt
Kaninchen
52
5
Klonalität
Polyklonal
Konjugat
Dieser PLA2G5 Antikörper ist unkonjugiert
8
8
7
2
2
2
Applikation
Western Blotting (WB)
48
39
22
6
5
2
1
Optionen
Hersteller
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Hersteller Produkt- Nr.
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Immunogen The immunogen is a synthetic peptide directed towards the middle region of human PLA2G5
Blocking Peptide Zu diesem Produkt passt das Blocking Peptide ABIN981830.
Sequenz YRFAWGVVTC EPGPFCHVNL CACDRKLVYC LKRNLRSYNP QYQYFPNILC
Homologie Cow: 86%, Dog: 93%, Guinea Pig: 86%, Horse: 85%, Human: 100%, Rat: 86%
Produktmerkmale This is a rabbit polyclonal antibody against PLA2G5. It was validated on Western Blot using a cell lysate as a positive control.
Reinigung Affinity Purified
Plasmids, Primers & others Plasmide, Primers & weitere PLA2G5 products on genomics-online (e.g. as negative or positive controls)
Antigen
Andere Bezeichnung PLA2G5 (PLA2G5 Antibody Abstract)
Hintergrund This gene is a member of the secretory phospholipase A2 family. It is located in a tightly-linked cluster of secretory phospholipase A2 genes on chromosome 1. The encoded enzyme catalyzes the hydrolysis of membrane phospholipids to generate lysophospholip
Alias Symbols: DKFZp686C2294, GV-PLA2, MGC46205, PLA2-10, hVPLA(2), FRFB
Protein Interaction Partner: PLA2G4A,
Protein Size: 138
Molekulargewicht 14 kDa
Gen-ID 5322
NCBI Accession NM_000929, NP_000920
UniProt P39877
Pathways Inositol Metabolic Process
Applikations-hinweise Optimal working dilutions should be determined experimentally by the investigator.
Kommentare

Antigen size: 138 AA

Beschränkungen Nur für Forschungszwecke einsetzbar
Format Liquid
Konzentration Lot specific
Buffer Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung Avoid repeated freeze-thaw cycles.
Lagerung -20 °C
Informationen zur Lagerung For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Bilder des Herstellers
Western Blotting (WB) image for anti-phospholipase A2, Group V (PLA2G5) (Middle Region) antibody (ABIN2776806) WB Suggested Anti-PLA2G5 Antibody Titration: 0.2-1 ug/ml ELISA Titer: 1:1562500 P...
Produkt verwendet in: Yamaguchi, Zacharia, Laidlaw, Balestrieri: "PLA2G5 regulates transglutaminase activity of human IL-4-activated M2 macrophages through PGE2 generation." in: Journal of leukocyte biology, Vol. 100, Issue 1, pp. 131-41, 2016 (PubMed).

Allgemeine Veröffentlichungen Wootton, Arora, Drenos, Thompson, Cooper, Stephens, Hurel, Hurt-Camejo, Wiklund, Humphries, Talmud: "Tagging SNP haplotype analysis of the secretory PLA2-V gene, PLA2G5, shows strong association with LDL and oxLDL levels, suggesting functional distinction from sPLA2-IIA: results from the UDACS study." in: Human molecular genetics, Vol. 16, Issue 12, pp. 1437-44, 2007 (PubMed).

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