PLA2G5 Antikörper (Middle Region)

Produktnummer ABIN2776806

Der Kaninchen Polyklonal Anti-PLA2G5-Antikörper wurde für WB validiert. Er ist geeignet, PLA2G5 in Proben von Ratte, Human, Rind (Kuh), Hund, Pferd und Meerschweinchen zu detektieren. Es ist 1 Publikation verfügbar.

Kurzübersicht für PLA2G5 Antikörper (Middle Region) (ABIN2776806)

Target: PLA2G5 (phospholipase A2, Group V (PLA2G5))

Reaktivität: Ratte, Human, Rind (Kuh), Hund, Pferd, Meerschweinchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PLA2G5 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-PLA2G5 Antikörper

Bindungsspezifität: Middle Region

Sequenz: YRFAWGVVTC EPGPFCHVNL CACDRKLVYC LKRNLRSYNP QYQYFPNILC

Homologie: Cow: 86%, Dog: 93%, Guinea Pig: 86%, Horse: 85%, Human: 100%, Rat: 86%

Produktmerkmale: This is a rabbit polyclonal antibody against PLA2G5. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human PLA2G5

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 138 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-PLA2G5 Antikörper (ABIN2776806)

Yamaguchi, Zacharia, Laidlaw, Balestrieri: "PLA2G5 regulates transglutaminase activity of human IL-4-activated M2 macrophages through PGE2 generation." in: Journal of leukocyte biology, Vol. 100, Issue 1, pp. 131-41, (2016) (PubMed).

Details zu PLA2G5

Target: PLA2G5 (phospholipase A2, Group V (PLA2G5))

Andere Bezeichnung: PLA2G5

Hintergrund: This gene is a member of the secretory phospholipase A2 family. It is located in a tightly-linked cluster of secretory phospholipase A2 genes on chromosome 1. The encoded enzyme catalyzes the hydrolysis of membrane phospholipids to generate lysophospholip
Alias Symbols: DKFZp686C2294, GV-PLA2, MGC46205, PLA2-10, hVPLA(2), FRFB
Protein Interaction Partner: PLA2G4A,
Protein Size: 138

Molekulargewicht: 14 kDa

Gen-ID: 5322

NCBI Accession: NM_000929, NP_000920

UniProt: P39877

Pathways: Inositol Metabolic Process