FZD4 Antikörper (C-Term)
Kurzübersicht für FZD4 Antikörper (C-Term) (ABIN2776714)
Target
Alle FZD4 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- C-Term
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Verwendungszweck
- FZD4 Antibody - C-terminal region
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Sequenz
- LDALTGFVVA PLFTYLVIGT LFIAAGLVAL FKIRSNLQKD GTKTDKLERL
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Homologie
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%
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Produktmerkmale
- This is a rabbit polyclonal antibody against GPCR. It was validated on Western Blot.
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Aufreinigung
- Affinity Purified
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Immunogen
- The immunogen is a synthetic peptide directed towards the C-terminal region of human FZD4
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Kommentare
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We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP41265-100UG
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 0.5 mg/mL
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Buffer
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- prevent freeze-thaw cycles
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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- FZD4 (Frizzled Family Receptor 4 (FZD4))
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Andere Bezeichnung
- FZD4
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Hintergrund
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Background Information: This gene is a member of the frizzled gene family. Members of this family encode seven-transmembrane domain proteins that are receptors for the Wingless type MMTV integration site family of signaling proteins. Most frizzled receptors are coupled to the beta-catenin canonical signaling pathway. This protein may play a role as a positive regulator of the Wingless type MMTV integration site signaling pathway. A transcript variant retaining intronic sequence and encoding a shorter isoform has been described, however, its expression is not supported by other experimental evidence.
Gene Name: frizzled class receptor 4
Alternative Symbols: Fz4, EVR1, FEVR, Fz-4, FzE4, GPCR, hFz4, CD344, FZD4S
Protein Name: frizzled-4
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Molekulargewicht
- 47kDa
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Gen-ID
- 8322
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NCBI Accession
- NP_036325
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UniProt
- Q9ULV1
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Pathways
- WNT Signalweg, Hormone Transport, Sensory Perception of Sound
Target
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