FZD10 Antikörper (N-Term)

Produktnummer ABIN2776713

Der Kaninchen Polyklonal Anti-FZD10-Antikörper wurde für WB validiert. Er ist geeignet, FZD10 in Proben von Human, Maus, Schwein, Rind (Kuh), Hund, Pferd und Zebrafisch (Danio rerio) zu detektieren. Es ist 1 Publikation verfügbar.

Kurzübersicht für FZD10 Antikörper (N-Term) (ABIN2776713)

Target: FZD10 (Frizzled Family Receptor 10 (FZD10))

Reaktivität: Human, Maus, Schwein, Rind (Kuh), Hund, Pferd, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FZD10 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-FZD10 Antikörper

Bindungsspezifität: N-Term

Sequenz: PIEIPMCKDI GYNMTRMPNL MGHENQREAA IQLHEFAPLV EYGCHGHLRF

Homologie: Cow: 100%, Dog: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Zebrafish: 79%

Produktmerkmale: This is a rabbit polyclonal antibody against FZD10. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human FZD10

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 581 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-FZD10 Antikörper (ABIN2776713)

Gonzalez, Fernandez-Martos, Gonzalez-Fernandez, Arenas, Rodriguez: "Spatio-temporal expression pattern of frizzled receptors after contusive spinal cord injury in adult rats." in: PLoS ONE, Vol. 7, Issue 12, pp. e50793, (2012) (PubMed).

Details zu FZD10

Target: FZD10 (Frizzled Family Receptor 10 (FZD10))

Andere Bezeichnung: FZD10

Hintergrund: FZD10 is a member of the frizzled family. Members of this family are 7-transmembrane domain proteins that are receptors for the Wingless type MMTV integration site family of signaling proteins. Most frizzled receptors are coupled to the beta-catenin canonical signaling pathway. Using array analysis, expression of this intronless gene is significantly up-regulated in two cases of primary colon cancer.This gene is a member of the frizzled gene family. Members of this family encode 7-transmembrane domain proteins that are receptors for the Wingless type MMTV integration site family of signaling proteins. Most frizzled receptors are coupled to the beta-catenin canonical signaling pathway. Using array analysis, expression of this intronless gene is significantly up-regulated in two cases of primary colon cancer.
Alias Symbols: FZ-10, FzE7, hFz10, Fz10, CD350
Protein Size: 581

Molekulargewicht: 65 kDa

Gen-ID: 11211

NCBI Accession: NM_007197, NP_009128

UniProt: Q9ULW2

Pathways: WNT Signalweg