FZD2 Antikörper (N-Term)

Produktnummer ABIN502077

Zitiert in 1 Publikation. Der Kaninchen Polyklonal anti-FZD2 Antikörper (ABIN502077) detektiert spezifisch FZD2 in WB. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Ratte, Maus, Rind (Kuh), Hund und Pferd.

Kurzübersicht für FZD2 Antikörper (N-Term) (ABIN502077)

Target: FZD2 (Frizzled Family Receptor 2 (FZD2))

Reaktivität: Human, Ratte, Maus, Rind (Kuh), Hund, Pferd

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FZD2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-FZD2 Antikörper

Bindungsspezifität: N-Term

Verwendungszweck: FZD2 Antibody - N-terminal region

Sequenz: MRPRSALPRL LLPLLLLPAA GPAQFHGEKG ISIPDHGFCQ PISIPLCTDI

Homologie: Cow: 100%, Dog: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against FZD2. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human FZD2

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP41236-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-FZD2 Antikörper (ABIN502077)

Li, Chen, Hu, Xing, Sasaki, Villosis, Li, Nishita, Minami, Minoo: "Ror2 modulates the canonical Wnt signaling in lung epithelial cells through cooperation with Fzd2." in: BMC molecular biology, Vol. 9, pp. 11, (2008) (PubMed).

Details zu FZD2

Target: FZD2 (Frizzled Family Receptor 2 (FZD2))

Andere Bezeichnung: FZD2

Hintergrund:

Background Information: Members of the 'frizzled' gene family encode 7-transmembrane domain proteins that are receptors for Wnt signaling proteins. The expression of the FZD2 gene appears to be developmentally regulated, with high levels of expression in fetal kidney and lung an

Gene Name: Frizzled family receptor 2

Alternative Symbols: Fz2, fz-2, fzE2, hFz2, OMOD2

Protein Name: Frizzled-2

Molekulargewicht: 63kDa

Gen-ID: 2535

NCBI Accession: NP_001457

UniProt: Q14332

Pathways: WNT Signalweg