HNRNPC Antikörper (N-Term)

Produktnummer ABIN2776586

Der Kaninchen Polyklonal Anti-HNRNPC-Antikörper wurde für WB validiert. Er ist geeignet, HNRNPC in Proben von Human, Ratte, Maus, Kaninchen, Hund und Schwein zu detektieren. Es ist 1 Publikation verfügbar.

Kurzübersicht für HNRNPC Antikörper (N-Term) (ABIN2776586)

Target: HNRNPC (Heterogeneous Nuclear Ribonucleoprotein C (C1/C2) (HNRNPC))

Reaktivität: Human, Ratte, Maus, Kaninchen, Hund, Schwein

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser HNRNPC Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-HNRNPC Antikörper

Bindungsspezifität: N-Term

Sequenz: LDINLAAEPK VNRGKAGVKR SAAEMYGSVT EHPSPSPLLS SSFDLDYDFQ

Homologie: Dog: 93%, Human: 100%, Mouse: 93%, Pig: 93%, Rabbit: 93%, Rat: 93%

Produktmerkmale: This is a rabbit polyclonal antibody against HNRPC. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human HNRPC

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 303 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-HNRNPC Antikörper (ABIN2776586)

Hayakawa, Fujikane, Ito, Matsumoto, Nakayama, Sekiguchi: "Human proteins that specifically bind to 8-oxoguanine-containing RNA and their responses to oxidative stress." in: Biochemical and biophysical research communications, Vol. 403, Issue 2, pp. 220-4, (2010) (PubMed).

Details zu HNRNPC

Target: HNRNPC (Heterogeneous Nuclear Ribonucleoprotein C (C1/C2) (HNRNPC))

Andere Bezeichnung: HNRPC

Hintergrund: HNRPC belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein can act as a tetramer and is involved in the assembly of 40S hnRNP particles.This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has one RRM domain that binds to RNAs. Two alternatively spliced transcript variants have been described for this gene.
Alias Symbols: C1, C2, HNRNP, MGC104306, MGC105117, MGC117353, MGC131677, SNRPC, hnRNPC, HNRPC
Protein Interaction Partner: SUMO1P1, RALYL, RBM41, ZFYVE26, SUMO1, UBE2I, UBC, SDCBP, LMO2, KPNA4, KPNA3, KPNA2, HNRNPC, EPS8, BRIP1, PALB2, BRCA2, BRCA1, BARD1, CEP250, SUMO2, SUMO3, RAD51, IVNS1ABP, STAU1, MDM2, ERG, EED, RNF2, rev, CDKN2A, PARK2, SRPK2, SRPK1, CLK3, TARDBP, YWHAQ
Protein Size: 303

Molekulargewicht: 33 kDa

Gen-ID: 3183

NCBI Accession: NM_031314, NP_112604

UniProt: P07910