HNRNPA2B1 Antikörper (N-Term)

Produktnummer ABIN2776584

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch HNRNPA2B1 in WB und IHC. Er zeigt eine Reaktivität gegenüber Human, Maus, Ratte, Schwein, Hund, Pferd, Kaninchen und Saccharomyces cerevisiae.

Kurzübersicht für HNRNPA2B1 Antikörper (N-Term) (ABIN2776584)

Target: HNRNPA2B1 (Heterogeneous Nuclear Ribonucleoprotein A2/B1 (HNRNPA2B1))

Reaktivität: Human, Maus, Ratte, Schwein, Hund, Pferd, Kaninchen, Saccharomyces cerevisiae

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser HNRNPA2B1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-HNRNPA2B1 Antikörper

Bindungsspezifität: N-Term

Sequenz: MEKTLETVPL ERKKREKEQF RKLFIGGLSF ETTEESLRNY YEQWGKLTDC

Homologie: Dog: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Yeast: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against HNRNPA2B1. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human HNRNPA2B1

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 353 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu HNRNPA2B1

Target: HNRNPA2B1 (Heterogeneous Nuclear Ribonucleoprotein A2/B1 (HNRNPA2B1))

Andere Bezeichnung: HNRNPA2B1

Hintergrund: HNRNPA2B1 belongs to the A/B subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. HNRNPA2B1 has two repeats of quasi-RRM domains that bind to RNAs.This gene belongs to the A/B subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has two repeats of quasi-RRM domains that bind to RNAs. This gene has been described to generate two alternatively spliced transcript variants which encode different isoforms.
Alias Symbols: DKFZp779B0244, FLJ22720, HNRNPA2, HNRNPB1, HNRPA2, HNRPA2B1, HNRPB1, RNPA2, SNRPB1
Protein Interaction Partner: PA2G4, HUWE1, UBC, TP53, AURKA, SUMO2, SUMO3, CDKN1A, NEDD1, HAUS1, CEP57, STAU1, SUMO1, NEDD8, MDM2, ERG, ASB2, RPA3, RPA2, RPA1, HNRNPL, EED, VHL, rev, RPL39, RPL27A, RAD51, QARS, PTBP1, PSMD13, PSMB4, PSMB1, PSMA6, PSMA5, PSMA4, PAFAH1B2, YBX1, MRE11A,
Protein Size: 353

Molekulargewicht: 37 kDa

Gen-ID: 3181

NCBI Accession: NM_031243, NP_112533

UniProt: P22626