MRPL24 Antikörper (N-Term)

Produktnummer ABIN2776572

Dieses Anti-MRPL24-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von MRPL24 in WB. Geeignet für Human, Maus, Ratte, Rind (Kuh), Hund, Meerschweinchen, Pferd und Kaninchen.

Kurzübersicht für MRPL24 Antikörper (N-Term) (ABIN2776572)

Target: MRPL24 (Mitochondrial Ribosomal Protein L24 (MRPL24))

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Meerschweinchen, Pferd, Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MRPL24 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-MRPL24 Antikörper

Bindungsspezifität: N-Term

Sequenz: RRRPVVVEPI SDEDWYLFCG DTVEILEGKD AGKQGKVVQV IRQRNWVVVG

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against MRPL24. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human MRPL24

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 216 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu MRPL24

Target: MRPL24 (Mitochondrial Ribosomal Protein L24 (MRPL24))

Andere Bezeichnung: MRPL24

Hintergrund: Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75 % protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. MRPL24 is a 39S subunit protein which is more than twice the size of its E.coli counterpart (EcoL24).Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75 % protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein which is more than twice the size of its E.coli counterpart (EcoL24). Sequence analysis identified two transcript variants that encode the same protein.
Alias Symbols: FLJ20917, MGC22737, MGC9831, MRP-L18, L24mt, MRP-L24
Protein Interaction Partner: TP53, AURKA, GRSF1, NPM1, MRPL21, C19orf70, MRPL45, TMEM177, MRPL44, MRPL40, MRPS5, TSR1, MRPL39, MRPL51, MRPL37, MRPL4, MRPL2, MRPL13, ERLEC1, MRPL19, TUFM, RPS15, ILF2, ABCC2, APP, CUL3, UBC, Ybx1, ICT1,
Protein Size: 216

Molekulargewicht: 25 kDa

Gen-ID: 79590

NCBI Accession: NM_024540, NP_078816

UniProt: Q96A35