UPF3A Antikörper (Middle Region)
Kurzübersicht für UPF3A Antikörper (Middle Region) (ABIN2776564)
Target
Alle UPF3A Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- Middle Region
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Sequenz
- QRYHVDDGRR HRAHHEPERL SRRSEDEQRW GKGPGQDRGK KGSQDSGAPG
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Homologie
- Human: 100%
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Produktmerkmale
- This is a rabbit polyclonal antibody against UPF3A. It was validated on Western Blot using a cell lysate as a positive control.
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Aufreinigung
- Affinity Purified
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Immunogen
- The immunogen is a synthetic peptide directed towards the middle region of human UPF3A
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Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
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Kommentare
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Antigen size: 476 AA
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- Lot specific
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid repeated freeze-thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- UPF3A (UPF3 Regulator of Nonsense Transcripts Homolog A (UPF3A))
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Andere Bezeichnung
- UPF3A
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Hintergrund
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UPF3A is part of a multiprotein post-splicing mRNP complex involved in both mRNA nuclear export and mRNA surveillance. UPF3A is involved in nonsense-mediated decay (NMD) of mRNAs containing premature stop codons. Binds spliced mRNA upstream of exon-exon j
Alias Symbols: HUPF3A, RENT3A, UPF3
Protein Interaction Partner: HTT, SMG1, HBB, APP, RNPS1, NXF1, SRRM1, TOPORS, PIGT, ALYREF, IFITM2, RBM8A, GSK3B, UPF1, UPF2, DCP2, UPF3B, EXOSC4, XRN1, EXOSC2, EXOSC10, PARN,
Protein Size: 476 -
Molekulargewicht
- 55 kDa
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Gen-ID
- 65110
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NCBI Accession
- NM_023011, NP_075387
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UniProt
- Q9H1J1
Target
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